Inhibition of porcine epidemic diarrhea virus replication and viral 3C-like protease by quercetin

Z Li, H Cao, Y Cheng, X Zhang, W Zeng, Y Sun… - International Journal of …, 2020 - mdpi.com
For the last decade, porcine epidemic diarrhea virus (PEDV) variant strains have caused
severe damage to the global pig industry. Until now, no effective antivirals have been …

Identification of two flavonoids antiviral inhibitors targeting 3C-like protease of porcine epidemic diarrhea virus

Z Li, L Zhu, L Wang, Y Huang, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) has caused severe damage to the global pig
industry in the past 20 years, creating an urgent demand for the development of associated …

Tomatidine inhibits porcine epidemic diarrhea virus replication by targeting 3CL protease

P Wang, J Bai, X Liu, M Wang, X Wang, P Jiang - Veterinary research, 2020 - Springer
Porcine epidemic diarrhea virus (PEDV) causes lethal diarrhea in suckling piglets, leading
to severe economic losses worldwide. There is an urgent need to find new therapeutic …

Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus

HJ Choi, JH Kim, CH Lee, YJ Ahn, JH Song, SH Baek… - Antiviral Research, 2009 - Elsevier
Porcine epidemic diarrhea virus (PEDV) is the predominant cause of severe entero-
pathogenic diarrhea in swine. The lack of effective therapeutical treatment underlines the …

Inhibitory effects of quercetin on porcine epidemic diarrhea virus in vitro and in vivo

T Gong, D Wu, Y Feng, X Liu, Q Gao, X Zheng, Z Song… - Virology, 2024 - Elsevier
Porcine epidemic diarrhea (PED) is an acute, severe, highly contagious disease. Porcine
epidemic diarrhea virus (PEDV) strains are prone to mutation, and the immune response …

Structural basis for inhibiting porcine epidemic diarrhea virus replication with the 3C-like protease inhibitor GC376

G Ye, X Wang, X Tong, Y Shi, ZF Fu, G Peng - Viruses, 2020 - mdpi.com
Porcine epidemic diarrhea virus (PEDV), being highly virulent and contagious in piglets, has
caused significant damage to the pork industries of many countries worldwide. There are no …

Quercetin 7-rhamnoside reduces porcine epidemic diarrhea virus replication via independent pathway of viral induced reactive oxygen species

JH Song, JK Shim, HJ Choi - Virology journal, 2011 - Springer
Background On the base of our previous study we were observed relevant studies on the
hypothesis that the antiviral activity of quercetin 7-rhamnoside (Q7R), a flavonoid, won't …

[HTML][HTML] Inhibition of porcine epidemic diarrhea virus by cinchonine via inducing cellular autophagy

J Ren, W Zeng, C Jiang, C Li, C Zhang… - Frontiers in Cellular …, 2022 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) could cause lethal diarrhea and dehydration in
suckling piglets, which can adversely affect the development of the global swine industry …

Epigallocatechin-3-Gallate, the Main Polyphenol in Green Tea, Inhibits Porcine Epidemic Diarrhea Virus In Vitro

C Huan, W Xu, B Ni, T Guo, H Pan, L Jiang… - Frontiers in …, 2021 - frontiersin.org
There are currently no licensed drugs against porcine epidemic diarrhea virus (PEDV), but
vaccines are available. We identified a natural molecule, epigallocatechin-3-gallate (EGCG) …

[HTML][HTML] Identification of niclosamide as a novel antiviral agent against porcine epidemic diarrhea virus infection by targeting viral internalization

Y Wang, H Huang, D Li, C Zhao, S Li, P Qin, Y Li… - Virologica Sinica, 2023 - Elsevier
Porcine epidemic diarrhea virus (PEDV), an enteropathogenic coronavirus, has catastrophic
impacts on the global pig industry. However, there remain no effective drugs against PEDV …