The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials

DT Felson, JJ Anderson, M Boers… - … : Official Journal of …, 1993 - Wiley Online Library
Objective. To develop a set of disease activity measures for use in rheumatoid arthritis (RA)
clinical trials, as well as to recommend specific methods for assessing each outcome …

[PDF][PDF] Provisional guidelines for measuring disease activity in clinical trials on rheumatoid arthritis

P Van Riel - Rheumatology, 1992 - researchgate.net
FOR many years disease activity in rheumatoid arthritis (RA) has been measured by an
enormous number of different variables as a single golden standard for measuring disease …

American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials

DT Felson, JS Smolen, G Wells, B Zhang… - Arthritis & …, 2011 - Wiley Online Library
Objective Remission in rheumatoid arthritis (RA) is an increasingly attainable goal, but there
is no widely used definition of remission that is stringent but achievable and could be …

Clinically important changes in individual and composite measures of rheumatoid arthritis activity: thresholds applicable in clinical trials

MM Ward, LC Guthrie, MI Alba - Annals of the rheumatic diseases, 2015 - ard.bmj.com
Objective Thresholds of minimal clinically important improvement (MCII) are needed to plan
and interpret clinical trials. We estimated MCIIs for the rheumatoid arthritis (RA) activity …

Reporting disease activity in clinical trials of patients with rheumatoid arthritis: EULAR/ACR collaborative recommendations

D Aletaha, R Landewe, T Karonitsch… - Arthritis Care & …, 2008 - Wiley Online Library
Objective To make recommendations on how to report disease activity in clinical trials of
rheumatoid arthritis (RA) endorsed by the European League Against Rheumatism (EULAR) …

Quantitative measures for assessing rheumatoid arthritis in clinical trials and clinical care

T Pincus, T Sokka - Best Practice & Research Clinical Rheumatology, 2003 - Elsevier
There is no single 'gold standard'quantitative measure to assess and monitor the clinical
status in patients with rheumatoid arthritis (RA). Therefore, a variety of measures have been …

Defining remission in rheumatoid arthritis

D Felson - Annals of the rheumatic diseases, 2012 - ard.bmj.com
Objective Given the inconsistency of remission definitions in rheumatoid arthritis (RA) trials,
the goal of this American College of Rheumatology/European League Against Rheumatism …

American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis

DT Felson, JJ Anderson, M Boers… - … : Official Journal of …, 1995 - Wiley Online Library
Objective. Trials of rheumatoid arthritis (RA) treatments report the average response in
multiple outcome measures for treated patients. It is more clinically relevant to test whether …

Validity of single variables and composite indices for measuring disease activity in rheumatoid arthritis.

DMFM van der Heijde, MA Van't Hof… - Annals of the …, 1992 - ard.bmj.com
There is no agreement as to which variable best mirrors disease activity in rheumatoid
arthritis (RA) and no studies have been performed on the validity of disease activity …

Clinical outcome measures in rheumatoid arthritis

PLCM van Riel, AM van Gestel - Annals of the rheumatic diseases, 2000 - ard.bmj.com
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease with peripheral
synovitis as its main manifestation. The presentation of the disease and the course during …