Benefits and limitations of porous substrates as biosensors for protein adsorption
Porous substrates have gained widespread interest for biosensor applications based on
molecular recognition. Thus, there is a great demand to systematically investigate the …
molecular recognition. Thus, there is a great demand to systematically investigate the …
Determination of association rate constants by an optical biosensor using initial rate analysis
PR Edwards, RJ Leatherbarrow - Analytical biochemistry, 1997 - Elsevier
We show that initial rate analysis can be successfully applied to analyze experimental
binding data generated by an optical biosensor. The initial rates of binding obtained from …
binding data generated by an optical biosensor. The initial rates of binding obtained from …
Analysis of mass transport-limited binding kinetics in evanescent wave biosensors
It is shown that currently used methods for analyzing surface plasmon resonance or
resonant mirror biosensor data do not adequately take into account the effects of mass …
resonant mirror biosensor data do not adequately take into account the effects of mass …
[PDF][PDF] BIACORE: an affinity biosensor system for characterization of biomolecular interactions
M Malmqvist - Biochemical society transactions, 1999 - researchgate.net
With the introduction of affinity biosensors for biomolecular interactions analysis (BIA) in
1990, a new concept for analysis of the functional properties of biomolecules was introduced …
1990, a new concept for analysis of the functional properties of biomolecules was introduced …
Continuous measurements of a binding reaction using a capacitive biosensor
M Hedström, IY Galaev, B Mattiasson - Biosensors and Bioelectronics, 2005 - Elsevier
A capacitive biosensor with polyclonal antibodies raised against human serum albumin
(HSA) immobilized on a gold transducer has been developed for continuous measurement …
(HSA) immobilized on a gold transducer has been developed for continuous measurement …
Kinetics of protein-protein interactions at the surface of an optical biosensor
PR Edwards, A Gill, DV Pollardknight, M Hoare… - Analytical …, 1995 - Elsevier
Methods based on the use of optical biosensors have recently become available to provide
a convenient means of determining the rate and equilibrium constants for bimolecular …
a convenient means of determining the rate and equilibrium constants for bimolecular …
[引用][C] Determination of effective diffusion coefficients—An important parameters for the efficiency of immobilized biocatalysts
P Grunwald - Biochemical education, 1989 - Elsevier
The limitation of mass transport by diffusion plays an important role in heterogeneous
catalysis especially when the insoluble catalyst has a porous structure. Therefore …
catalysis especially when the insoluble catalyst has a porous structure. Therefore …
Modeling Taylor dispersion injections: determination of kinetic/affinity interaction constants and diffusion coefficients in label-free biosensing
JG Quinn - Analytical biochemistry, 2012 - Elsevier
A new method based on Taylor dispersion has been developed that enables an analyte
gradient to be titrated over a ligand-coated surface for kinetic/affinity analysis of interactions …
gradient to be titrated over a ligand-coated surface for kinetic/affinity analysis of interactions …
Future trends in biosensor research
PJ O'Connell, GG Guilbault - Analytical letters, 2001 - Taylor & Francis
The past few years have seen a dramatic change in biosensor technology. This change can
be attributed to the convergence of three different strands of research: a. Researchers have …
be attributed to the convergence of three different strands of research: a. Researchers have …
Comparative analyses of a small molecule/enzyme interaction by multiple users of Biacore technology
MJ Cannon, GA Papalia, I Navratilova, RJ Fisher… - Analytical …, 2004 - Elsevier
To gauge the experimental variability associated with Biacore analysis, 36 different
investigators analyzed a small molecule/enzyme interaction under similar conditions …
investigators analyzed a small molecule/enzyme interaction under similar conditions …