A review of the thermodynamics of protein association to ligands, protein adsorption, and adsorption isotherms

JM Mollerup - Chemical Engineering & Technology: Industrial …, 2008 - Wiley Online Library
The application of thermodynamic models in the development of chromatographic
separation processes is discussed. The paper analyses the thermodynamic principles of …

The difference interferometer: application as a direct affinity sensor

D Schlatter, R Barner, C Fattinger, W Huber… - Biosensors and …, 1993 - Elsevier
This paper describes the application of a novel sensor technology for determining the
concentration of biologically and diagnostically relevant analytes with high sensitivity and …

Direct immunochemical sensing: basic chemical principles and fundamental limitations

MJ Eddowes - Biosensors, 1987 - Elsevier
Abstract Models describing the binding of antigens to surface immobilised antibodies have
been developed. These models are applied to the assessment of the likely analytical utility …

[图书][B] Handbook of biosensors and biosensor kinetics

A Sadana, N Sadana - 2010 - books.google.com
Biosensors are essential to an ever-expanding range of applications, including healthcare;
drug design; detection of biological, chemical, and toxic agents; environmental monitoring; …

[HTML][HTML] Evaluation of Taylor dispersion injections: determining kinetic/affinity interaction constants and diffusion coefficients in label-free biosensing

JG Quinn - Analytical biochemistry, 2012 - Elsevier
In label-free biomolecular interaction analysis, a standard injection provides an injection of
uniform analyte concentration. An alternative approach exploiting Taylor dispersion …

Protein-sensing assay formats and devices

U Bilitewski - Analytica chimica acta, 2006 - Elsevier
Proteins are used as biocatalysts, therapeutic or diagnostic agents, and as such they are
biotechnological products. Moreover, they are biomarkers for health states, diseases or toxic …

Protein adsorption and leakage in carrier–enzyme systems

R Ulbrich, R Golbik… - Biotechnology and …, 1991 - Wiley Online Library
The capability of binding enzymes adsorptively to unmodified and silanized silica and glass
as well as modified polystyrene carriers was studied for α‐amylase, β‐amylase, and α …

Estimation of diffusion coefficients of proteins

ME Young, PA Carroad, RL Bell - Biotechnology and …, 1980 - Wiley Online Library
A correlation for estimating the diffusion coefficients of protein molecules is presented. The
correlation is based upon literature values of the protein diffusion coefficients and molal …

New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin

E Lázaro, PJ Lowe, X Briand… - Journal of medicinal …, 2008 - ACS Publications
We report here a new, label-free approach to measure serum protein binding constants. The
assay is able to measure HSA K d values in the milli-molar to micromolar range. The protein …