Synthesis and evaluation of new thiazolyl hydrazone derivatives as potential anticancer agents
Z Asım Kaplancıklı, B Sever… - Letters in Drug …, 2017 - ingentaconnect.com
Background: In recent years, thiazole derivatives incorporated with hydrazone moiety have
attracted a great deal of interest due to their pivotal role in the field of current cancer …
attracted a great deal of interest due to their pivotal role in the field of current cancer …
[HTML][HTML] Synthesis and in vitro evaluation of new nitro-substituted thiazolyl hydrazone derivatives as anticandidal and anticancer agents
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their
anticandidal activity using a broth microdilution assay. Among the synthesized compounds …
anticandidal activity using a broth microdilution assay. Among the synthesized compounds …
Synthesis and biological evaluation of new pyrazole-based thiazolyl hydrazone derivatives as potential anticancer agents
M Dilek Altıntop, A Ozdemir, S Ilgın… - Letters in Drug Design & …, 2014 - ingentaconnect.com
New pyrazole-based thiazolyl hydrazone derivatives were obtained via the ring closure
reaction of 3, 5-dimethyl-1H-1-phenylpyrazole-4-carboxaldehyde thiosemicarbazone with 2 …
reaction of 3, 5-dimethyl-1H-1-phenylpyrazole-4-carboxaldehyde thiosemicarbazone with 2 …
A facile access and evaluation of some novel thiazole and 1, 3, 4-thiadiazole derivatives incorporating thiazole moiety as potent anticancer agents
Background Many heterocyclic compounds containing thiazole or 1, 3, 4-thiadiazole ring in
their skeletons have been reported to possess various pharmacological activities especially …
their skeletons have been reported to possess various pharmacological activities especially …
Synthesis, antitumor activity and mechanism of action of novel 1, 3-thiazole derivatives containing hydrazide–hydrazone and carboxamide moiety
H He, X Wang, L Shi, W Yin, Z Yang, H He… - Bioorganic & medicinal …, 2016 - Elsevier
Abstract A series of novel 2, 4, 5-trisubstituted 1, 3-thiazole derivatives containing hydrazide–
hydrazine, and carboxamide moiety including 46 compounds T were synthesized, and …
hydrazine, and carboxamide moiety including 46 compounds T were synthesized, and …
Design and efficient synthesis of novel 4, 5-dimethylthiazole-hydrazone derivatives and their anticancer activity
Background: Recently, researchers have been warning about the increased mortality of the
various cancer types. Also, the lung adenocarcinoma and the glioma types are burning …
various cancer types. Also, the lung adenocarcinoma and the glioma types are burning …
Synthesis and biological evaluation of new quinoline-based thiazolyl hydrazone derivatives as potent antifungal and anticancer agents
Background: In medicinal chemistry, thiazoles have gained great importance in antifungal
and anticancer drug design and development. Objectives: The aim of this study was to …
and anticancer drug design and development. Objectives: The aim of this study was to …
Synthesis, characterization and molecular docking of novel bioactive thiazolyl-thiazole derivatives as promising cytotoxic antitumor drug
SM Gomha, TA Salaheldin, HME Hassaneen… - Molecules, 2015 - mdpi.com
Reactions of ethylidenethiocarbohydrazide with hydrazonoyl halides gave 1, 3-thiazole or 1,
3, 4-thiadiazole derivatives according to the type of hydrazonoyl halides. Treatment of …
3, 4-thiadiazole derivatives according to the type of hydrazonoyl halides. Treatment of …
Synthesis and biological evaluation of thiazolyl-ethylidene hydrazino-thiazole derivatives: a novel heterocyclic system
LA Al-Mutabagani, FM Abdelrazek, SM Gomha… - Applied Sciences, 2021 - mdpi.com
The reaction of 2-(1-(2-(2-(4-methoxybenzylidene) hydrazinyl)-4-methylthiazol-5-yl)
ethylidene) hydrazinecarbothioamide with a range of hydrazonoyl chlorides and α-halo …
ethylidene) hydrazinecarbothioamide with a range of hydrazonoyl chlorides and α-halo …
Synthesis, molecular docking and antiproliferative activity studies of a thiazole‐based compound linked to hydrazone moiety
Abstract (A new 4‐oxothiazolidin‐2‐ylidene derivative bearing hydrazone moiety was
synthesized via Michael addition between the reaction of 4‐(4‐nitrophenyl)‐3 …
synthesized via Michael addition between the reaction of 4‐(4‐nitrophenyl)‐3 …