DNA methylation and chromatin–unraveling the tangled web
KD Robertson - Oncogene, 2002 - nature.com
Methylation of cytosines within the CpG dinucleotide by DNA methyltransferases is involved
in regulating transcription and chromatin structure, controlling the spread of parasitic …
in regulating transcription and chromatin structure, controlling the spread of parasitic …
Genomic DNA methylation: the mark and its mediators
Methylation of DNA at position five of the cytosine ring occurs at most CpG dinucleotides in
the mammalian genome and is essential for embryonic viability. With several of the key …
the mammalian genome and is essential for embryonic viability. With several of the key …
DNA methylation and gene expression
Z Siegfried, I Simon - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
Methylation of cytosines is the key epigenetic modification of DNA in eukaryotes and is
associated with a repressed chromatin state and inhibition of gene expression. The …
associated with a repressed chromatin state and inhibition of gene expression. The …
DNA methylation: past, present and future directions
KD Robertson, P A. Jones - Carcinogenesis, 2000 - academic.oup.com
DNA methylation, or the covalent addition of a methyl group to cytosine within the context of
the CpG dinucleotide, has profound effects on the mammalian genome. These effects …
the CpG dinucleotide, has profound effects on the mammalian genome. These effects …
DNA methylation‐mediated epigenetic control
A Rottach, H Leonhardt, F Spada - Journal of cellular …, 2009 - Wiley Online Library
During differentiation and development cells undergo dramatic morphological and functional
changes without any change in the DNA sequence. The underlying changes of gene …
changes without any change in the DNA sequence. The underlying changes of gene …
The interplay between DNA and histone methylation: molecular mechanisms and disease implications
Methylation of cytosine in CpG dinucleotides and histone lysine and arginine residues is a
chromatin modification that critically contributes to the regulation of genome integrity …
chromatin modification that critically contributes to the regulation of genome integrity …
DNA methylation, methyltransferases, and cancer
KD Robertson - Oncogene, 2001 - nature.com
The field of epigenetics has recently moved to the forefront of studies relating to diverse
processes such as transcriptional regulation, chromatin structure, genome integrity, and …
processes such as transcriptional regulation, chromatin structure, genome integrity, and …
DNA methylation and DNA methyltransferases
JR Edwards, O Yarychkivska, M Boulard… - Epigenetics & …, 2017 - Springer
The prevailing views as to the form, function, and regulation of genomic methylation patterns
have their origin many years in the past, at a time when the structure of the mammalian …
have their origin many years in the past, at a time when the structure of the mammalian …
DNA methylation and cancer
PC Taberlay, PA Jones - Epigenetics and Disease: Pharmaceutical …, 2011 - Springer
DNA methylation acts in concert with other epigenetic mechanisms to regulate normal gene
expression and facilitate chromatin organization within cells. Aberrant DNA methylation …
expression and facilitate chromatin organization within cells. Aberrant DNA methylation …
DNA methylation: superior or subordinate in the epigenetic hierarchy?
B Jin, Y Li, KD Robertson - Genes & cancer, 2011 - journals.sagepub.com
Epigenetic modifications are heritable changes in gene expression not encoded by the DNA
sequence. In the past decade, great strides have been made in characterizing epigenetic …
sequence. In the past decade, great strides have been made in characterizing epigenetic …
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