Experimental autoimmune encephalomyelitis (EAE) is a CD4+ T cell-mediated, inflammatory
demyelinating disease of the central nervous system (CNS) that serves as a model for …

Experimental autoimmune encephalomyelits (EAE) has been widely studied as a model for
multiple sclerosis (MS). EAE also holds a special place in basic autoimmune research. It is …

Multiple sclerosis (MS) is a complex disease with many different immune cells involved in its
pathogenesis, and in particular T cells as the most recognized cell type. Recently, the innate …

Multiple sclerosis (MS) is one of the most common neurological disorders in young adults.
The etiology of MS is not known but it is widely accepted that it is autoimmune in nature …

Objectives: We investigated proinflammatory M1 and immunomodulatory M2 activation
profiles of circulating monocytes in relapsing experimental autoimmune encephalomyelitis …

Myelin phagocytosis by macrophages has been an essential feature of demyelinating
diseases in the central and peripheral nervous systems, including Guillain–Barré syndrome …

Multiple sclerosis (MS) is a debilitating autoimmune disease characterized by both
inflammation and axonal degeneration. The resulting demyelination and subsequent …

Studies aimed to elucidate the pathogenesis of the disease and to find new therapeutic
options for multiple sclerosis (MS) patients heavily rely on experimental autoimmune …

Recent studies revealed an important involvement of the cerebral cortex in multiple sclerosis
(MS) patients. Cortical lesions in MS were reported to be less inflammatory and to show less …

In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS),
which may at later times transform into secondary progressive disease (SPMS). In a minority …