Comparative effectiveness of postoperative chemotherapy among older patients with non-metastatic rectal cancer treated with preoperative chemoradiotherapy

JL Lund, T Sturmer, HK Sanoff - Journal of geriatric oncology, 2016 - Elsevier
Objective Postoperative chemotherapy is standard following preoperative chemoradiation
therapy (CRT) and curative resection for clinically staged II/III rectal cancer. Recent trials …

[HTML][HTML] Clinical outcomes of preoperative chemoradiotherapy in octogenarian with locally advanced rectal cancer

T Nishikawa, K Kawai, K Hata… - Molecular and …, 2019 - spandidos-publications.com
The number of elderly patients who receive surgical treatment for rectal cancer has
gradually increased with aging of the population. In recent years, preoperative …

Preoperative chemoradiotherapy for elderly patients with locally advanced rectal cancer—a real-world outcome study

Y Choi, JH Kim, JW Kim, JW Kim… - Japanese Journal of …, 2016 - academic.oup.com
Objective Preoperative chemoradiotherapy has been established as a standard treatment
for locally advanced rectal cancer. It is unclear whether preoperative chemoradiotherapy is …

Role of Radical Surgery Following Preoperative Chemoradiotherapy in Octogenarians With Rectal Cancer: A SEER Analysis

YJ Lim, M Kong - Anticancer Research, 2024 - ar.iiarjournals.org
Background/Aim: There has been a growing trend toward a watch-and-wait strategy to avoid
surgery. This study evaluated the prognostic outcomes of nonoperative management …

Postoperative chemotherapy use after neoadjuvant chemoradiotherapy for rectal cancer: Analysis of Surveillance, Epidemiology, and End Results–Medicare data …

AB Haynes, YN You, CY Hu, C Eng, ES Kopetz… - Cancer, 2014 - Wiley Online Library
BACKGROUND Neoadjuvant chemoradiotherapy followed by tumor resection and
postoperative chemotherapy is the standard of care for patients with clinical stage II or III …

Preoperative chemoradiotherapy for rectal cancer in patients aged 75 years and older: acute toxicity, compliance with treatment, and early results

V Guimas, J Boustani, B Schipman, N Lescut… - Drugs & aging, 2016 - Springer
Purpose Treatment of locally advanced rectal cancer (T3–T4 or N+) is based on short-
course radiotherapy (RT) or chemoradiotherapy (CRT) followed by surgery. It is estimated …

Is chemotherapy or radiation therapy in addition to surgery beneficial for locally advanced rectal cancer in the elderly? A National Cancer Data Base (NCDB) Study

JR Bergquist, CA Thiels, CR Shubert… - World journal of …, 2016 - Springer
Abstract Introduction Current National Comprehensive Cancer Network guidelines for
Stages II and III rectal cancer recommend neoadjuvant chemoradiation followed by curative …

Oncologic outcome and morbidity in the elderly rectal cancer patients after preoperative chemoradiotherapy and total mesorectal excision: a multi-institutional and …

SY Sung, HS Jang, SH Kim, JU Jeong, S Jeong… - Annals of …, 2019 - journals.lww.com
Objective: To determine the toxicity and oncologic outcome of neoadjuvant
chemoradiotherapy (CRT) followed by curative total mesorectal excision (TME) in the elderly …

Safety and efficacy of preoperative chemoradiotherapy in fit older patients with intermediate or locally advanced rectal cancer evaluated by comprehensive geriatric …

WY Liu, J Jin, Y Tang, N Li, Y Tang, J Wang… - Journal of Geriatric …, 2021 - Elsevier
Background and purpose Comprehensive geriatric assessment (CGA) is a diagnostic
method to assess the physical and mental health status of older patients. The purpose of this …

Tolerability of combined modality therapy for rectal cancer in elderly patients aged 75 years and older

DN Margalit, HJ Mamon, M Ancukiewicz… - International Journal of …, 2011 - Elsevier
PURPOSE: To determine the rate of treatment deviations during combined modality therapy
for rectal cancer in elderly patients aged 75 years and older. METHODS AND MATERIALS …