Angiotensin receptor blockers: therapeutic targets and cardiovascular protection

LM Ruilope, EA Rosei, GL Bakris, G Mancia… - Blood …, 2005 - Taylor & Francis
In the prevention and treatment of cardiovascular disease, pharmacological treatment
strategies should have several aims:(i) in individuals without overt cardiovascular disease …

Angiotensin converting enzyme inhibitors in hypertension: potential problems

TFT Antonios, GA MacGregor - Journal of Hypertension, 1995 - journals.lww.com
Angiotensin converting enzyme inhibitors in hypertension: po... : Journal of Hypertension
Angiotensin converting enzyme inhibitors in hypertension: potential problems : Journal of …

ACE-Inhibitors in Hypertension: A historical perspective and current insights

S Cutrell, IS Alhomoud, A Mehta, AH Talasaz… - Current hypertension …, 2023 - Springer
Abstract Purpose of Review This review describes the discovery and development of ACE
inhibitors as antihypertensive agents, compares their efficacy, tolerability, and safety to …

Systematic review of combined angiotensin-converting enzyme inhibition and angiotensin receptor blockade in hypertension

TWR Doulton, FJ He, GA MacGregor - Hypertension, 2005 - Am Heart Assoc
Some evidence suggests that long-term angiotensin-converting enzyme (ACE) inhibition
may become less effective, thereby increasing angiotensin II levels, which could be inhibited …

Blood pressure-dependent and independent effects of agents that inhibit the renin–angiotensin system

Blood Pressure Lowering Treatment Trialists' … - Journal of …, 2007 - journals.lww.com
Objectives To evaluate the blood pressure-dependent and independent effects of
angiotensin-converting enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) …

First‐line drugs inhibiting the renin angiotensin system versus other first‐line antihypertensive drug classes for hypertension

YJ Chen, LJ Li, WL Tang, JY Song… - Cochrane database …, 2018 - cochranelibrary.com
Background This is the first update of a Cochrane Review first published in 2015. Renin
angiotensin system (RAS) inhibitors include angiotensin converting enzyme (ACE) …

Rationale, design, and baseline characteristics of 2 large, simple, randomized trials evaluating telmisartan, ramipril, and their combination in high-risk patients: the …

Ontarget/transcend Investigators - American heart journal, 2004 - Elsevier
BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors reduce mortality,
myocardial infarction, stroke, heart failure, need for revascularization, nephropathy, and …

A review of ACE inhibitors and ARBs in black patients with hypertension

A Helmer, N Slater, S Smithgall - Annals of …, 2018 - journals.sagepub.com
Objective: To review current guidelines and recent data evaluating the efficacy and safety of
angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) …

Angiotensin receptor blockers: pharmacology, efficacy, and safety

AA Taylor, H Siragy, S Nesbitt - The Journal of Clinical …, 2011 - Wiley Online Library
J Clin Hypertens (Greenwich). 2011; 13: 677–686.© 2011 Wiley Periodicals, Inc. Key Points
and Practical Recommendations• The angiotensin receptor blockers are highly effective …

Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors or angiotensin II–receptor blockers for ischemic heart disease

WL Baker, CI Coleman, J Kluger… - Annals of internal …, 2009 - acpjournals.org
Background: Patients with ischemic heart disease and preserved ventricular function
experience considerable morbidity and mortality despite standard medical therapy. Purpose …