The transport and kinetic processes describing biomolecular interactions in the BIACORE
optical biosensor have been studied with the help of a mathematical model. In comparison …

Optical biosensors, including the BIACORE, provide an increasingly popular method for
determining reaction rates of biomolecules. In a flow chamber, with one reactant …

The binding kinetics recorded for many interactions using BIAcore and IAsys optical
biosensors do not fit a simple bimolecular interaction model (A+ B⇄ AB). Three methods of …

The theory of a method for determining active concentration of nonpurified protein samples
using the BIAcore biosensor technology has been developed. The method relies on change …

The mass-transfer processes that affect kinetic measurements of biospecific interactions
between one species in a flowing solution and another species immobilized in a thin …

Optical biosensors provide a platform for qualitatively and quantitatively analyzing various
biomolecular interactions. In addition to advantages such as label-free and high-throughput …

An important step in the analysis of sensorgram data for BIAcore experiments is the
subtraction of reference cell data to remove the effects of the bulk shift on the sensorgram of …

I examined the penetration of the hydrodynamic flow into a polymer matrix immobilized by
grafting to a surface, such as used in optical biosensors designed to measure binding …

In the Biacore biosensor, a widely used tool for studying the kinetics of ligand/receptor
binding, receptors are commonly localized to the sensor surface through attachment to …

The advent of commercial optical biosensors, such as the BIAcore from Pharmacia and
IAsys from Affinity Sensors, has made available to the biochemist a powerful means to …