[HTML][HTML] Multivalent 9-O-Acetylated-sialic acid glycoclusters as potent inhibitors for SARS-CoV-2 infection
The recent emergence of highly transmissible SARS-CoV-2 variants illustrates the urgent
need to better understand the molecular details of the virus binding to its host cell and to …
need to better understand the molecular details of the virus binding to its host cell and to …
The role of cell surface sialic acids for SARS-CoV-2 infection
XL Sun - Glycobiology, 2021 - academic.oup.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a new virus that has
higher contagious capacity than any other previous human coronaviruses (HCoVs) and …
higher contagious capacity than any other previous human coronaviruses (HCoVs) and …
[HTML][HTML] Significant role of host sialylated glycans in the infection and spread of severe acute respiratory syndrome coronavirus 2
W Saso, M Yamasaki, S Nakakita, S Fukushi… - PLoS …, 2022 - journals.plos.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been transmitted
across all over the world, in contrast to the limited epidemic of genetically-and virologically …
across all over the world, in contrast to the limited epidemic of genetically-and virologically …
[HTML][HTML] Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2
Emerging evidence suggests that host glycans influence severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. Here, we reveal that the receptor-binding domain …
coronavirus 2 (SARS-CoV-2) infection. Here, we reveal that the receptor-binding domain …
[HTML][HTML] Subtle influence of ACE2 glycan processing on SARS-CoV-2 recognition
The severity of SARS-CoV-2 infection is highly variable and yet the molecular basis for this
effect remains elusive. One potential contribution are differences in the glycosylation of …
effect remains elusive. One potential contribution are differences in the glycosylation of …
Leveraging coronavirus binding to gangliosides for innovative vaccine and therapeutic strategies against COVID-19
Covid-19 is an infectious respiratory disease due to a coronavirus named SARS-CoV-2. A
critical step of the infection cycle is the binding of the virus spike S protein to the cellular ACE …
critical step of the infection cycle is the binding of the virus spike S protein to the cellular ACE …
Surface glycan modification of cellular nanosponges to promote SARS-CoV-2 inhibition
Cellular binding and entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) are mediated by its spike glycoprotein (S protein), which binds with not only the human …
2) are mediated by its spike glycoprotein (S protein), which binds with not only the human …
[HTML][HTML] SARS-CoV-2 evolutionary adaptation toward host entry and recognition of receptor O-Acetyl sialylation in virus–host interaction
CH Kim - International journal of molecular sciences, 2020 - mdpi.com
The recently emerged SARS-CoV-2 is the cause of the global health crisis of the coronavirus
disease 2019 (COVID-19) pandemic. No evidence is yet available for CoV infection into …
disease 2019 (COVID-19) pandemic. No evidence is yet available for CoV infection into …
[HTML][HTML] The sialoside-binding pocket of SARS-CoV-2 spike glycoprotein structurally resembles MERS-CoV
COVID-19 novel coronavirus (CoV) disease caused by severe acquired respiratory
syndrome (SARS)-CoV-2 manifests severe lethal respiratory illness in humans and has …
syndrome (SARS)-CoV-2 manifests severe lethal respiratory illness in humans and has …
Effective inhibition of SARS-CoV-2 entry by heparin and enoxaparin derivatives
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has caused a
pandemic of historic proportions and continues to spread globally, with enormous …
pandemic of historic proportions and continues to spread globally, with enormous …