Management of glioblastoma: State of the art and future directions
Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for
patients with this disease is poor, with a median survival of< 2 years. There is a slight …
patients with this disease is poor, with a median survival of< 2 years. There is a slight …
New approaches to glioblastoma
M Khasraw, Y Fujita, C Lee-Chang… - Annual review of …, 2022 - annualreviews.org
Faced with unique immunobiology and marked heterogeneity, treatment strategies for
glioblastoma require therapeutic approaches that diverge from conventional oncological …
glioblastoma require therapeutic approaches that diverge from conventional oncological …
Emerging therapies for glioblastoma
AA Thomas, CW Brennan, LM DeAngelis… - JAMA …, 2014 - jamanetwork.com
Importance Glioblastoma is the most common primary malignant brain tumor, but despite
multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the …
multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the …
Management of glioblastoma, present and future
NAO Bush, SL Hervey-Jumper, MS Berger - World neurosurgery, 2019 - Elsevier
Glioblastomas are the most common malignant brain tumor and despite extensive research
have a dismal prognosis. This review focuses on the current treatment paradigms of …
have a dismal prognosis. This review focuses on the current treatment paradigms of …
[HTML][HTML] The landscape of novel therapeutics and challenges in glioblastoma multiforme: contemporary state and future directions
K Khaddour, TM Johanns, G Ansstas - Pharmaceuticals, 2020 - mdpi.com
Background: Glioblastoma multiforme is a malignant intracranial neoplasm that constitutes a
therapeutic challenge because of the associated high morbidity and mortality given the lack …
therapeutic challenge because of the associated high morbidity and mortality given the lack …
[HTML][HTML] Emerging therapies for glioblastoma: current state and future directions
L Rong, N Li, Z Zhang - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an
extremely poor prognosis. Given the poor survival with currently approved treatments for …
extremely poor prognosis. Given the poor survival with currently approved treatments for …
[HTML][HTML] Therapy for glioblastoma: is it working?
ED Zanders, F Svensson, DS Bailey - Drug discovery today, 2019 - Elsevier
Highlights•As of July 2018, there were 759 ongoing or projected clinical trials for
glioblastoma.•Drug therapies appear compromised by the need to combat tumour …
glioblastoma.•Drug therapies appear compromised by the need to combat tumour …
Key clinical principles in the management of glioblastoma
R Kotecha, Y Odia, AA Khosla, MS Ahluwalia - JCO oncology practice, 2023 - ascopubs.org
Glioblastoma is the most common and aggressive primary brain tumor in the adult
population and leads to considerable morbidity and mortality. It has a dismal prognosis with …
population and leads to considerable morbidity and mortality. It has a dismal prognosis with …
[HTML][HTML] Advances in glioblastoma therapy: an update on current approaches
Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …
[HTML][HTML] Glioblastoma update: molecular biology, diagnosis, treatment, response assessment, and translational clinical trials
F Lieberman - F1000Research, 2017 - ncbi.nlm.nih.gov
This is an exciting time in neuro-oncology. Discoveries elucidating the molecular
mechanisms of oncogenesis and the molecular subtypes of glioblastoma multiforme (GBM) …
mechanisms of oncogenesis and the molecular subtypes of glioblastoma multiforme (GBM) …