[PDF][PDF] The retinoblastoma binding protein 6 family is essential for embryonic development and carcinogenesis
Regulators of the tumour suppressor protein, p53 are promising anti-cancer drug
candidates. The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, has …
candidates. The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, has …
[HTML][HTML] Expression, purification, and characterisation of the p53 binding domain of Retinoblastoma binding protein 6 (RBBP6)
BL Russell, M Ntwasa - Plos one, 2023 - journals.plos.org
RBBP6 is a 250 kDa eukaryotic protein known to be a negative regulator of p53 and
essential for embryonic development. Furthermore, RBBP6 is a critical element in …
essential for embryonic development. Furthermore, RBBP6 is a critical element in …
Retinoblastoma binding protein 6, another p53 monitor
M Ntwasa - Trends in cancer, 2016 - cell.com
The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, is essential for
embryonic development. Its loss-of-function phenotype is similar to mouse double minute …
embryonic development. Its loss-of-function phenotype is similar to mouse double minute …
[PDF][PDF] The retinoblastoma binding protein 6 is a potential target for therapeutic drugs
M Ntwasa - Biotechnol. Mol. Biol. Rev, 2008 - academia.edu
The retinoblastoma binding protein 6 (RBBP6) proteins (also called P-53 Associated Cell
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …
[HTML][HTML] Unveiling the molecular structure and role of RBBP4/7: implications for epigenetic regulation and cancer research
L Cai, B Liu, Y Cao, T Sun, Y Li - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Retinoblastoma-binding protein (RBBP) family is a class of proteins that can interact with
tumor suppressor retinoblastoma protein (pRb). RBBP4 and RBBP7 are the only pair of …
tumor suppressor retinoblastoma protein (pRb). RBBP4 and RBBP7 are the only pair of …
Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)
RBBP4 is a nuclear WD40 motif-containing protein widely implicated in various cancers and
a putative drug target. It interacts with multiple proteins within diverse complexes such as …
a putative drug target. It interacts with multiple proteins within diverse complexes such as …
Expression and function of retinoblastoma binding protein 6 (RBBP6) in human lung cancer
LR Motadi, KD Bhoola, Z Dlamini - Immunobiology, 2011 - Elsevier
Retinoblastoma binding protein 6 (RBBP6) interacts with both p53 and pRb, and has been
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …
Expression Analysis of RbBP6 in human cancers: a Prospective biomarker
Abstract Retinoblastoma binding protein 6 (RBBP6) is a cancer-related protein that has
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …
[PDF][PDF] Implications of RBBP6 in various types of cancer.
Background: The 2 50 k Da r etinoblastoma bi nding pr otein 6 (RBBP6) was cloned over a
decade ago and was found to bind both the p53 and Rb1 tumor suppressor proteins. In …
decade ago and was found to bind both the p53 and Rb1 tumor suppressor proteins. In …
Retinoblastoma binding protein 5 correlates with the progression in hepatocellular carcinoma
H Zhou, J Bao, X Zhu, G Dai, X Jiang… - BioMed research …, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common malignancy tumors with
insidious onset, rapid development and metastasis, and poor prognosis. Therefore, it is …
insidious onset, rapid development and metastasis, and poor prognosis. Therefore, it is …