Interleukin (IL)-8 is a macrophage-derived neutrophil chemotactic factor that plays an
important role in the recruitment of neutrophils to inflammatory loci. Hence, expression of IL …

Inflammatory cytokines, including interleukin (IL)-1 α, IL-1 β, IL-8, and tumor necrosis factor α
(TNF-α) are produced by macrophages in response to a variety of pathogenic stimuli. We …

IL-1 beta is the major form of IL-1 produced by mononuclear phagocytes. To evaluate the
possible mechanisms underlying the observation that mature populations of human …

Interleukin-6 (IL-6) is a pleiotropic cytokine that regulates the immune response, acute-
phase reaction, and hematopoiesis. As a first step in studying the actions of IL-6 in pigs, the …

Cellular constituents of the alveolar-capillary wall may be key participants in the recruitment
of polymorphonuclear leukocytes to the lung through the generation of the novel neutrophil …

Materials and Methods Reagents and Probes LPS, actinomycin D, polymyxin B, and
dexamethasone were purchased from Sigma Chemical Co.(St. Louis, MO). LPS …

Human alveolar macrophages (AM) are antigen-presenting cells that have an important
immune effector function in the lung. We have previously shown that AM produce a specific …

Reverse transcription-polymerase chain reaction (RT-PCR) with interleukin-1alpha (IL-1α)-
specific primers using total RNA from lipopolysaccharide (LPS)-stimulated lung …

Our previous work demonstrated that hypoxia decreases transcription of the human
prostaglandin H synthase-2 (PGHS-2) gene during exposure to lipopolysaccharide (LPS) …

Although peritoneal resident macrophages (PRM) or peritoneal exudate macrophages
(PEM) were activated by lipopolysaccharide (LPS) to kill tumor cells in vitro, lung …