Ex vivo expansion of hematopoietic stem cells (HSCs) is important for many clinical
applications, and knowledge of the surface phenotype of ex vivo–expanded HSCs will be …

A better understanding of the biology of cultured hematopoietic stem cells (HSCs) is
required to achieve ex vivo expansion of HSCs. In this study, clonal analysis of the surface …

In the mouse, over the last 20 years, a set of cell‐surface markers and activities have been
identified, enabling the isolation of bone marrow (BM) populations highly enriched in …

Attempts to improve hematopoietic reconstitution and engraftment potential of ex vivo–
expanded hematopoietic stem and progenitor cells (HSPCs) have been largely …

Abstract Treatment with a combination of cytokines and chemotherapy can effectively
stimulate the release of hematopoietic stem cells (HSC) into the peripheral blood (PB) …

Little is known about how hematopoietic stem cells (HSCs) self-renew. We studied the
regeneration of HSCs in culture. Effects of various cytokines on cell division of CD34−/low c …

OBJECTIVES: The relationship between phenotype and function in ex vivo–cultured human
hematopoietic stem cells (HSC) remains poorly understood. We investigated the effects of a …

The marrow repopulating potential (MRP) of different sources of human hematopoietic stem
cells (HSCs) was directly compared using an in vivo assay in which severe combined …

Hematopoietic stem cells (HSCs) cultured outside the body are the fundamental component
of a wide range of cellular and gene therapies. Recent efforts have achieved> 200‐fold …

Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that
recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor …