Human iPS cell–derived hematopoietic progenitor cells induce T-cell anergy in in vitro–generated alloreactive CD8+ T cells

EM Kim, G Manzar, N Zavazava - Blood, The Journal of the …, 2013 - ashpublications.org
Human induced pluripotent stem cells (iPSCs) have emerged as an alternative source of
pluripotent stem cells that can be used for tissue regeneration in place of the controversial …

Generation of antigen-specific T cells from human induced pluripotent stem cells

T Nishimura, H Nakauchi - Immunological Tolerance: Methods and …, 2019 - Springer
Human induced pluripotent stem cells (iPSCs) are a potential source of blood cells for
transfusion therapies and a promising tool for studying the ontogeny of hematopoiesis. The …

Pluripotent stem cells: immune to the immune system?

JI Pearl, LS Kean, MM Davis, JC Wu - Science translational medicine, 2012 - science.org
Human embryonic stem cells (hESCs), initially thought to be immune privileged cells, are
now known to be susceptible to immune recognition. Human induced pluripotent stem cells …

Generation of immune cells from induced pluripotent stem cells (iPSCs): Their potential for adoptive cell therapy

M Gheitasi, S Safdel, SK Patra, R Zandvakili… - Human Immunology, 2024 - Elsevier
Advances in human stem cell technologies enable induced pluripotent stem cells (iPSCs) to
be explored as potent candidates for treating various diseases, such as malignancies …

Derivation of transgene-free human induced pluripotent stem cells from human peripheral T cells in defined culture conditions

Y Kishino, T Seki, J Fujita, S Yuasa, S Tohyama… - PloS one, 2014 - journals.plos.org
Recently, induced pluripotent stem cells (iPSCs) were established as promising cell sources
for revolutionary regenerative therapies. The initial culture system used for iPSC generation …

Humanized mice reveal differential immunogenicity of cells derived from autologous induced pluripotent stem cells

T Zhao, Z Zhang, PD Westenskow, D Todorova, Z Hu… - Cell stem cell, 2015 - cell.com
The breakthrough of induced pluripotent stem cell (iPSC) technology has raised the
possibility that patient-specific iPSCs may become a renewable source of autologous cells …

Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells

P Guha, JW Morgan, G Mostoslavsky, NP Rodrigues… - Cell stem cell, 2013 - cell.com
The prospects for using autologous induced pluripotent stem cells (iPSCs) in cell
replacement therapy have been tempered by evidence that undifferentiated, syngeneic …

Induced pluripotent stem cells can effectively differentiate into multiple functional lymphocyte lineages in vivo with negligible bias

T Lan, L Wang, L Xu, N Jin, G Yan, J Xia… - Stem Cells and …, 2016 - liebertpub.com
Lymphohematopoietic stem cells (L-HSCs) generated from self-somatic cell-derived induced
pluripotent stem cells (iPSCs) are a potential source of cells for the treatment of …

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

G Amabile, RS Welner… - Blood, The Journal …, 2013 - ashpublications.org
Lineage-restricted cells can be reprogrammed to a pluripotent state known as induced
pluripotent stem (iPS) cells through overexpression of 4 transcription factors. iPS cells are …

Induced pluripotent stem cell (iPSCs) and their application in immunotherapy

Z Jiang, Y Han, X Cao - Cellular & molecular immunology, 2014 - nature.com
The ever-improving technology to generate induced pluripotent stem cells (iPSCs) has
increased their potential use as novel candidates for disease modeling, drug screening …