Captopril versus atenolol to prevent expansion rate of thoracic aortic aneurysms: rationale and design

M Spartalis, E Tzatzaki, DC Iliopoulos… - Future …, 2020 - Future Medicine
Thoracic aortic aneurysms are correlated with significant mortality and morbidity. No therapy,
however, is effective at limiting aneurysm expansion and preventing rupture. Angiotensin …

Risk reduction and pharmacological strategies to prevent progression of aortic aneurysms

G Weininger, SM Chan, M Zafar… - Expert Review of …, 2021 - Taylor & Francis
Introduction While size thresholds exist to determine when aortic aneurysms warrant
surgical intervention, there is no consensus on how best to treat this disease before …

Clinical and patho-anatomical factors affecting expansion of thoracic aortic aneurysms

RS Bonser, D Pagano, ME Lewis, SJ Rooney, P Guest… - Heart, 2000 - heart.bmj.com
OBJECTIVE To examine the expansion of aneurysmal aortic segments (⩾ 35 mm) and to
assess the impact of clinical and patho-anatomical factors on aneurysm expansion. DESIGN …

[HTML][HTML] Treatment of thoracic aortic aneurysm

WS Aronow - Annals of translational medicine, 2018 - ncbi.nlm.nih.gov
The diameter of thoracic aortic aneurysm (AA) is at least 1.5 times that of a normal thoracic
aorta (1). Sixty percent of thoracic AAs occur in the aortic root and/or the ascending aorta …

[HTML][HTML] Systematic review of the growth rates and influencing factors in thoracic aortic aneurysms

D Oladokun, BO Patterson, J Sobocinski… - European Journal of …, 2016 - Elsevier
Objective/Background The growth rates of thoracic aortic aneurysms (TAAs) and factors
influencing their expansion are poorly understood. This study aimed to review systematically …

Medical therapy of thoracic aortic aneurysms

P Danyi, JA Elefteriades, IS Jovin - Trends in cardiovascular medicine, 2012 - Elsevier
Thoracic aortic aneurysm is a major health problem with multiple etiologies and potentially
devastating consequences. Currently, no large randomized trial has shown that medical …

[HTML][HTML] Pharmacological interventions to attenuate the expansion of abdominal aortic aneurysm (AAA)–a systematic review

D Bergqvist - European Journal of Vascular and Endovascular …, 2011 - Elsevier
INTRODUCTION: Is it possible by pharmacological methods to attenuate the expansion rate
of abdominal aortic aneurysms? METHOD: An Internet-based systematic literature search …

Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm

B Liu, DJ Granville, J Golledge… - American Journal of …, 2020 - journals.physiology.org
Aortic aneurysm is a permanent focal dilation of the aorta. It is usually an asymptomatic
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …

Does medical therapy for thoracic aortic aneurysms really work? Are β-blockers truly indicated? CON

SL Liao, S Elmariah, S van der Zee… - Cardiology …, 2010 - cardiology.theclinics.com
Thoracic aortic aneurysms (TAA) often represent the final manifestation of hereditary or
degenerative disease processes. TAA are primarily caused by age-related degenerative …

The efficacy of pharmacotherapy for decreasing the expansion rate of abdominal aortic aneurysms: a systematic review and meta-analysis

I Guessous, D Periard, D Lorenzetti, J Cornuz… - PLoS …, 2008 - journals.plos.org
Background Pharmacotherapy may represent a potential means to limit the expansion rate
of abdominal aortic aneurysms (AAAs). Studies evaluating the efficacy of different …