The retinoblastoma binding protein 6 (RBBP6) proteins (also called P-53 Associated Cell
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …

Regulators of the tumour suppressor protein, p53 are promising anti-cancer drug
candidates. The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, has …

RBBP6 is a 250 kDa eukaryotic protein known to be a negative regulator of p53 and
essential for embryonic development. Furthermore, RBBP6 is a critical element in …

Retinoblastoma binding protein 6 (RBBP6) interacts with both p53 and pRb, and has been
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …

The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, is essential for
embryonic development. Its loss-of-function phenotype is similar to mouse double minute …

The human retinoblastoma binding protein 6 (RBBP6) is implicated in esophageal, lung,
hepatocellular and colon cancers. Furthermore, RBBP6 was identified as a strong marker for …

As a step towards better integrating protein three-dimensional (3D) structural information in
cancer systems biology, the Northeast Structural Genomics Consortium (NESG)(www. nesg …

Abstract Retinoblastoma binding protein 6 (RBBP6) is a cancer-related protein that has
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …

In malignant melanomas, the loss of cell cycle control is thought to be due to a lack of
retinoblastoma protein (pRb)-activity. Members of the previously described family of …

RBBP4 is a nuclear WD40 motif-containing protein widely implicated in various cancers and
a putative drug target. It interacts with multiple proteins within diverse complexes such as …