Objectives: Most cases of irresolvable hoarseness are due to deficiencies in the pliability
and volume of the superficial lamina propria of the phonatory mucosa. By using a US Food …

Objectives Scarred vocal folds result in irregular vibrations during phonation due to stiffness
of the vocal fold mucosa. To date, a completely satisfactory corrective procedure has yet to …

Objectives/Hypothesis The purpose of this study was to develop and provide evidence of a
novel permanent injectable biomaterial for vocal fold augmentation with the potential to treat …

Objectives/Hypothesis Vocal fold scar is a major cause of dysphonia, and optimal treatments
do not currently exist. Small intestinal submucosa (SIS) is a biomaterial developed for the …

The current treatment options for dysphonia secondary to vocal fold scarring are limited. Few
studies address changes in the lamina propria, which is critical to vocal fold biomechanical …

Gel-based injectable biomaterials have significant potential for treating vocal fold defects
such as scarring. An ideal injectable for vocal fold lamina propria restoration should mimic …

Scarring of the vocal fold lamina propria can lead to debilitating voice disorders that can
significantly impair quality of life. The reduced pliability of the scar tissue—which diminishes …

Objectives: To measure the viscoelastic shear properties of hyaluronic acid, with and without
fibronectin, and to compare them with those of the human vocal fold mucosa and other …

Objectives: A prospective, controlled animal study was performed to determine whether the
use of injectable, chemically modified hyaluronic acid (HA) derivatives at the time of …

There is increasing demand for reconstruction of glottal insufficiency. Several injection
materials have been examined for this purpose, but all had limitations, such as poor long …