RBBP6: a potential biomarker of apoptosis induction in human cervical cancer cell lines

P Moela, LR Motadi - OncoTargets and therapy, 2016 - Taylor & Francis
Overexpression of RBBP6 in cancers of the colon, lung, and esophagus makes it a potential
target in anticancer therapy. This is especially important because RBBP6 associates with the …

RBBP6 is abundantly expressed in human cervical carcinoma and may be implicated in its malignant progression

Z Dlamini, T Ledwaba, R Hull, S Naicker… - Biomarkers in …, 2019 - journals.sagepub.com
RBBP6 is a novel gene encoding splicing-associated proteins. There are 3 protein isoforms
(isoforms 1-3). RBBP6 isoforms 1 has been shown to interact with both p53 and Rb. It also …

Expression Analysis of RbBP6 in human cancers: a Prospective biomarker

Z Mbita, R Hull, M Mbele, T Makhafola… - Anti-Cancer …, 2019 - journals.lww.com
Abstract Retinoblastoma binding protein 6 (RBBP6) is a cancer-related protein that has
been implicated in the regulation of cell cycle and apoptosis. RBBP6 isoform 1 has been …

Expression analysis and association of RBBP6 with apoptosis in colon cancers

Z Dlamini, C Rupnarain, S Naicker, R Hull… - Journal of molecular …, 2016 - Springer
Apoptosis is normally kept under strict control by a range of regulators and inhibitors, and
loss of this regulation strongly directs tumour progression. The novel RBBP6 gene has been …

RBBP6 expressional effects on cell proliferation and apoptosis in breast cancer cell lines with distinct p53 statuses

LR Motadi, MM Lekganyane… - Cancer Management and …, 2018 - Taylor & Francis
Introduction Breast cancer is the most common malignancy amongst women and has a
higher incidence rate than lung cancer. Its tumor progression partially results from …

Overexpression of RBBP6, alone or combined with mutant TP53, is predictive of poor prognosis in colon cancer

J Chen, H Tang, Z Wu, C Zhou, T Jiang, Y Xue… - PloS one, 2013 - journals.plos.org
Retinoblastoma binding protein 6 (RBBP6) plays an important role in chaperone-mediated
ubiquitination and interacts with TP53 in carcinogenesis. However, the clinicopathologic …

[PDF][PDF] Functional analysis and characterization of the human RBBP6 promoters based on a combination of molecular biology and in silico approaches provide …

A Pretorius, M Kaur, M Wamalwa, MF February… - J. Biosci, 2013 - academia.edu
Retinoblastoma Binding Protein 6 (RBBP6) has been implicated in the apoptotic pathway
and regulation of the cell cycle through its interaction with p53, Rb and YB1 and …

RBBP6 induces non-small cell lung cancer cell proliferation and high expression is associated with poor prognosis

QS Wang, SR Wei, HL Xiao - Oncology Letters, 2020 - spandidos-publications.com
Lung cancer is the most common cause of cancer-associated mortality in China with 85% of
patients having non-small cell lung cancer (NSCLC). Identifying NSCLC driver genes and …

[HTML][HTML] RBP7 is a clinically prognostic biomarker and linked to tumor invasion and EMT in colon cancer

M Elmasry, L Brandl, J Engel, A Jung, T Kirchner… - Journal of …, 2019 - ncbi.nlm.nih.gov
RBP7 is a member of the cellular retinol-binding protein (CRBP) family and previous data
suggested a link between CRBPs and the malignant transformation of colon cancer cells …

[HTML][HTML] RBBP6 promotes human cervical carcinoma malignancy via JNK signaling pathway

F Teng, HJ Ruan, J Xu, J Ni, B Qian, R Shen… - Biomedicine & …, 2018 - Elsevier
Previous studies have shown that retinoblastoma binding protein 6 (RBBP6) was
overexpressed in malignant tumors and was correlated with poorer prognosis in various …