Capsaicin: Selective toxicity for thin primary sensory neurons

P Holzer - Selective Neurotoxicity, 1992 - Springer
Capsaicin is the pungent ingredient in a wide variety of red peppers of the genus Capsicum.
Chemically it is a derivative of vanillyl amide, 8-methyl-N-vanillyl-6-nonenamide (Fig. 1) with …

Capsaicin and sensory neurones—a review

M Fitzgerald - Pain, 1983 - Elsevier
In the late fifties and sixties Jancso published a series of papers on 'the peculiar
pharmacological effect of capsaicin Capsaicin or 8-methyl-N-vanillyi-6-nonenamide is the …

Capsaicin's action on the nervous system

JI Nagy - Trends in Neurosciences, 1982 - cell.com
Over the past several decades capsaicin, a natural product of certain species of red pepper,
has been found to have a broad range of physiological effects in adult animals. Recent …

[引用][C] Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons.

P Holzer - Pharmacological reviews, 1991 - ASPET
THE function of primary afferent neurons is to receive and transmit information from the
internal and external environment and thereby contribute to the organism's ability to …

Capsaicin: a probe for studying specific neuronal populations in brain and retina

S Ritter, TT Dinh - Methods in Neurosciences, 1992 - Elsevier
Publisher Summary This chapter discusses that capsaicin can be a valuable tool for
chemical dissection of highly specific neural subsystems within the brain and retina. It also …

Characterization of the peptide and sensory neurotoxic effects of capsaicin in the guinea pig

SH Buck, JH Walsh, TP Davis, MR Brown… - Journal of …, 1983 - Soc Neuroscience
The effects of capsaicin, the major pungent ingredient of hot peppers, were assessed on
sensory neuron neuropeptide levels and on sensory function in the adult guinea pig …

Capsaicin: a chemical probe for sensory neuron mechanisms

JI Nagy - Handbook of Psychopharmacology: Volume 15 New …, 1982 - Springer
Capsaicin is a principle constituent in a large variety of red peppers (eg, Capsicum annuum,
Capsicum frutescens), and it is to this and closely related substances that the pungency of …

The ionic basis of capsaicin-evoked responses

S Bevan, RJ Docherty - Neurogenic Inflammation. CRC Press …, 1996 - books.google.com
Capsaicin, the pungent ingredient from peppers of the Capsicum family, has been widely
exploited as a tool in sensory neuron biology and the study of neurogenic inflammation. Its …

1-1) Neurotoxicity and long lasting analgesia induced by Capsaicinoids

SS LEE, YW SOHN, ES YOO, KH KIM - The Journal of toxicological …, 1991 - jstage.jst.go.jp
SUMMARY Administration of capsaicin (8—methyl—N-vanilly1—6—nonenamide) to
neonatal rats gives a long—lasting insensitivity to chemical irritants, and its potential as a …

The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro

SJ Marsh, CE Stansfeld, DA Brown, R Davey… - Neuroscience, 1987 - Elsevier
The selective excitant and neurotoxic action of capsaicin on vagal sensory neurons in the rat
has been investigated in vitro using three techniques: extracellular recording of compound …