Objective Recent studies have pointed to neuroinflammation and neurotrophic factors as
crucial mediators in the pathophysiology origins of mood disorders. The aim of this review is …

Objectives Recent studies have pointed to neuroinflammation, oxidative stress and
neurotrophic factors as key mediators in the pathophysiology of mood disorders. Little is …

Background Bipolar disorder (BD) has been associated with cognitive impairment during
depressed, manic and euthymic periods. Inflammation has been shown to be involved in the …

Background Systemic inflammation-immune dysregulation and brain abnormalities are
believed to contribute to the pathogenesis of bipolar disorder (BD). However, the …

Background The various pharmacological interventions, ranging from mood stabilizers and
antipsychotics to antidepressants, reflect the diff/iculty of treating depressive/manic …

Bipolar disorder (BD) is a severe and recurrent neuropsychiatric illness that causes high
rates of disability, with onset frequently during adolescence and early adulthood (Barnett …

Bipolar disorder (BD) is a multifactorial chronic psychiatric disease highly defined by
genetic, clinical, environmental and social risk factors. The present systematic review and …

Data support the notion that 40–60% of patients with bipolar disorder (BD) have
neurocognitive deficits. It is increasingly accepted that functioning in BD is negatively …

Bipolar disorder (BD) is a multifactorial chronic psychiatric disease highly defined by
genetic, clinical, environmental and social risk factors. The present systematic review and …

Background Bipolar disorder (BD) is a common affective disorder characterized by recurrent
oscillations between mood states and associated with inflammatory diseases and chronic …