Abstract Background: The porcine species (Sus scrofa domesticus) has had a great impact
as a source of food worldwide, but also it is a very useful animal for biomedical applications …

Pigs are an important resource for meat production and serve as a model for human
diseases. Due to their physiological and anatomical similarities to humans, these animals …

Abstract Genome/gene-editing (GE) techniques, characterized by a low technological
barrier, high efficiency, and broad application among organisms, are now being employed …

Genome modification technology of livestock has developed rapidly in recent years. We can
not only insert foreign genes or DNA into a specific locus or disrupt an endogenous locus by …

The generation of genetically engineered (GE) pigs for disease modeling and
xenotransplantation has been massively facilitated by the discovery of the CRISPR/Cas9 …

Pigs provide valuable meat sources, disease models, and research materials for humans.
However, traditional methods no longer meet the developing needs of pig production. More …

Traditionally, genetic engineering in the pig was a challenging task. Genetic engineering of
somatic cells followed by somatic cell nuclear transfer (SCNT) could produce genetically …

Due to recent innovations in gene editing technology, great progress has been made in
livestock breeding, with researchers rearing gene-edited pigs, cattle, sheep, and other …

Genome editing is a powerful technology that can efficiently alter the genome of organisms
to achieve targeted modification of endogenous genes and targeted integration of …

Nuclease-mediated genome editing technologies contribute to the rapid advances in life
sciences via the ability to edit the genomes within living cells, and present a new era for …