There is growing evidence that environmental toxicants can affect various physiological
processes by altering DNA methylation patterns. However, very little is known about the …

Abstract Benzo [a] pyrene (BaP) is an established carcinogen and reproductive and
developmental toxicant. BaP exposure in humans and animals has been linked to infertility …

Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …

DNA methylation is important for gene regulation and is vulnerable to early-life exposure to
environmental contaminants. We found that direct waterborne benzo [a] pyrene (BaP) …

A number of chemicals have been shown to affect epigenetic patterning and functions. Since
epigenetic mechanisms regulate transcriptional networks, epigenetic changes induced by …

There is increasing evidence that toxicant exposure can alter DNA methylation profile, one
of the main epigenetic mechanisms, particularly during embryogenesis when DNA …

Early molecular events with correlation to disease, such as aberrant DNA methylation,
emphasize the importance of DNA methylation as a potential environmental biomarker …

Background Exposure to environmental stressors during development may lead to latent
and transgenerational adverse health effects. To understand the role of DNA methylation in …

Altered DNA methylation is associated with changes in gene expression, signal transduction
and stress response after exposure to a wide range of exogenous compounds, and …

The DNA methylation landscape is dynamically patterned during development and distinct
methylation patterns distinguish healthy from diseased cells. However, whether tissue …