Large-scale evaluation of the immuno-mycologics lateral flow and enzyme-linked immunoassays for detection of cryptococcal antigen in serum and cerebrospinal fluid

J Hansen, ES Slechta… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
Cryptococcosis is a systemic infection caused by the pathogenic yeasts Cryptococcus
neoformans and C. gattii. Detection of cryptococcal capsular antigen (CrAg) in serum and …

Clinical utility of the cryptococcal antigen lateral flow assay in a diagnostic mycology laboratory

BJ McMullan, C Halliday, TC Sorrell, D Judd… - PLoS …, 2012 - journals.plos.org
Background Cryptococcus neoformans causes life-threatening meningitis. A recently
introduced lateral flow immunoassay (LFA) to detect cryptococcal antigen (CRAG) is …

Low cryptococcus antigen titers as determined by lateral flow assay should be interpreted cautiously in patients without prior diagnosis of cryptococcal infection

M Dubbels, D Granger, ES Theel - Journal of Clinical …, 2017 - Am Soc Microbiol
ABSTRACT Detection of Cryptococcus antigen (CrAg) is invaluable for establishing
cryptococcal disease. Multiple different methods for CrAg detection are available, including …

Comparison of four assays for the detection of cryptococcal antigen

MJ Binnicker, DJ Jespersen, JE Bestrom… - Clinical and Vaccine …, 2012 - Am Soc Microbiol
We compared the performance of four assays for the detection of cryptococcal antigen in
serum samples (n= 634) and cerebrospinal fluid (CSF) samples (n= 51). Compared to latex …

Comparison of commercial kits for detection of cryptococcal antigen

DC Tanner, MP Weinstein, B Fedorciw… - Journal of clinical …, 1994 - Am Soc Microbiol
Although kits to detect cryptococcal antigen are used widely to diagnose cryptococcal
infection, the comparative performance of commercially available assays has not been …

Evaluation of a new cryptococcal antigen lateral flow immunoassay in serum, cerebrospinal fluid and urine for the diagnosis of cryptococcosis: a meta-analysis and …

HR Huang, LC Fan, B Rajbanshi, JF Xu - PLoS One, 2015 - journals.plos.org
Background A new lateral flow immunoassay (LFA) for the detection of cryptococcal antigen
was developed. Objective We aimed to systematically review all relevant studies to evaluate …

Point-of-care diagnosis and prognostication of cryptococcal meningitis with the cryptococcal antigen lateral flow assay on cerebrospinal fluid

T Kabanda, MJ Siedner, JD Klausner… - Clinical infectious …, 2014 - academic.oup.com
The cryptococcal antigen (CRAG) lateral flow assay (LFA) had 100% sensitivity and
specificity on cerebrospinal fluid samples. Pretreatment LFA titers correlated with …

Pitfalls in Serological Diagnosis of Cryptococcus gattii Infections

K Tintelnot, F Hagen, CO Han, M Seibold… - Medical …, 2015 - academic.oup.com
The detection of cryptococcal antigen by latex agglutination tests (LATs), enzyme-linked
immunoassays (ELISA), or lateral flow assay (LFA) is an important tool for diagnosis of a …

Evaluation of serum cryptococcal antigen testing using two novel semiquantitative lateral flow assays in persons with cryptococcal antigenemia

C Skipper, K Tadeo, E Martyn, E Nalintya… - Journal of clinical …, 2020 - Am Soc Microbiol
Early cryptococcal disease can be detected via circulating antigen in blood before fulminant
meningitis develops, when early antifungal therapy improves survival. Two semiquantitative …

[HTML][HTML] Sensitivity and specificity of a new cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid

JD Klausner, T Vijayan, T Chiller - MLO: medical laboratory …, 2013 - ncbi.nlm.nih.gov
Methods We conducted a review of published literature and conference abstracts through
August 21, 2012, to identify studies on the performance of the LFA in serum and CSF …