Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …

Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …

Increasing recurrence of mammalian tumors and severe side-effects of chemotherapeutic
agents reduce the clinical efficacy of a large variety of anticancer agents that are currently …

Background: Cancer is a disease characterized by uncontrolled cell growth and
proliferation. It has become a major health problem in the past decades and is now the …

Until the end of the 19th century all drugs were natural products or minerals. During the 19th
century chemists succeeded in isolating pure natural products such as quinine, morphine …

Alkaloids are important chemical compounds that serve as a rich reservoir for drug
discovery. Several alkaloids isolated from natural herbs exhibit antiproliferation and …

Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …

The use of dimeric" Vinca" alkaloids in cancer therapy together with the clinical evaluation of
camptothecin and Cephalotaxus alkaloids in China mark alkaloids as an especially …

Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They
are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have …

Cancer still represents a “nightmare” worldwide, causing annually millions of victims.
Several antiproliferative molecules are currently used as drugs market and offer a …