Monitoring cytotoxic T lymphocyte (CTL) responses to tumor antigens that have been
defined at the molecular level has become essential to assess novel approaches to the …

Advances in immunological monitoring provide the means to analyse the cellular immune
response with greater sensitivity and precision than ever before. Novel immunological tools …

Evidence of adaptive immune responses in the prevention of cancer has been accumulating
for decades. Spontaneous T-cell responses occur in multiple indications, bringing the study …

Characterizing the interaction of cancer cells with the host adaptive immune system is critical
for understanding tumor immunology and the modus operandi of immunotherapeutic …

Immunotherapy has become one of the most promising avenues for cancer treatment,
making use of the patient's own immune system to eliminate cancer cells. Clinical trials with …

Cytotoxic T cells recognize, via their T cell receptors (TCRs), small antigenic peptides
presented by the major histocompatibility complex (pMHC) on the surface of professional …

Immunotherapies are at the forefront of the fight against cancers, and researchers continue
to develop and test novel immunotherapeutic modalities. Ideal cancer immunotherapies …

Advances in immune profiling techniques have dramatically changed the cancer
immunotherapy and monitoring landscape. High-throughput protein and gene expression …

The disappointing clinical results of cancer immunotherapy of the past few decades have not
diminished the optimism about the potential of the new generation of immunotherapeutic …

Numerous cancer immunotherapy strategies are currently being tested in clinical trials.
Although clinical efficacy will be the final test of these approaches, the long and complicated …