Effects of inhaled corticosteroids on airway inflammation in chronic obstructive pulmonary disease: a systematic review and meta-analysis

R Jen, SI Rennard, DD Sin - International journal of chronic …, 2012 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic
inflammation in the small airways. The effect of inhaled corticosteroids (ICS) on lung …

Effects of inhaled corticosteroids on sputum cell counts in stable chronic obstructive pulmonary disease: a systematic review and a meta-analysis

WQ Gan, SFP Man, DD Sin - BMC pulmonary medicine, 2005 - Springer
Background Whether inhaled corticosteroids suppress airway inflammation in chronic
obstructive pulmonary disease (COPD) remains controversial. We sought to determine the …

Inhaled corticosteroids and risk of pneumonia in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials

M Yang, Y Du, H Chen, D Jiang, Z Xu - International immunopharmacology, 2019 - Elsevier
Objective Inhaled corticosteroids (ICS) are generally used to treat patients with chronic
obstructive pulmonary disease (COPD) who suffer from repeated exacerbations. Recently, it …

Airway inflammation in COPD after long-term withdrawal of inhaled corticosteroids

LIZ Kunz, NHT Ten Hacken… - European …, 2017 - Eur Respiratory Soc
Long-term treatment with inhaled corticosteroids (ICS) might attenuate lung function decline
and decrease airway inflammation in a subset of patients with chronic obstructive pulmonary …

The effects of inhaled and oral corticosteroids on serum inflammatory biomarkers in COPD: an exploratory study

SFP Man, X Zhang, R Vessey… - Therapeutic …, 2009 - journals.sagepub.com
Background: Several studies suggest that inhaled and oral corticosteroids repress systemic
inflammation in chronic obstructive pulmonary disease (COPD). However, the cytokines that …

Use of inhaled corticosteroids in COPD: improving efficacy

IA Yang, JG Shaw, JR Goddard… - Expert review of …, 2016 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a chronic, inflammatory lung disease
characterized by airflow limitation that is not fully reversible. The pathological changes in …

Inhaled corticosteroids and the pneumonia risk in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials

H Chen, J Sun, Q Huang, Y Liu, M Yuan… - Frontiers in …, 2021 - frontiersin.org
Background: Whether all types of inhaled corticosteroids (ICSs) would increase the
pneumonia risk in patients with chronic obstructive pulmonary disease (COPD) remains …

Inhaled and systemic corticosteroids in chronic obstructive pulmonary disease

JA Falk, OA Minai, Z Mosenifar - Proceedings of the American …, 2008 - atsjournals.org
Systemic and local inflammation is central to the pathophysiology of chronic obstructive
pulmonary disease (COPD). Increased levels of inflammation have been linked to a more …

The effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review of randomized placebo-controlled trials

A Alsaeedi, DD Sin, FA McAlister - The American journal of medicine, 2002 - Elsevier
PURPOSE: Although inhaled corticosteroids are commonly used to treat patients with
chronic obstructive pulmonary disease (COPD), their effect on clinical outcomes such as …

[HTML][HTML] Sputum inflammation predicts exacerbations after cessation of inhaled corticosteroids in COPD

JJW Liesker, E Bathoorn, DS Postma, JM Vonk… - Respiratory …, 2011 - Elsevier
INTRODUCTION: The GOLD guidelines advocate not to institute inhaled corticosteroids
(ICS) in patients with mild-to-moderate COPD. However, many patients do use ICS and in …