The roles of macrophages and microglia in multiple sclerosis and experimental autoimmune encephalomyelitis
F Chu, M Shi, C Zheng, D Shen, J Zhu, X Zheng… - Journal of …, 2018 - Elsevier
Multiple sclerosis (MS) is an autoimmune and neurodegenerative disorder characterized by
chronic inflammation, demyelination, as well as axonal and neuronal loss in the central …
chronic inflammation, demyelination, as well as axonal and neuronal loss in the central …
Macrophages: a double-edged sword in experimental autoimmune encephalomyelitis
Z Jiang, JX Jiang, GX Zhang - Immunology letters, 2014 - Elsevier
Multiple sclerosis (MS) is a debilitating neurological disorder of the central nervous system
(CNS), characterized by activation and infiltration of leukocytes and dendritic cells into the …
(CNS), characterized by activation and infiltration of leukocytes and dendritic cells into the …
Microglia in central nervous system inflammation and multiple sclerosis pathology
Microglia are the resident macrophages of the central nervous system (CNS). They have
important physiological functions in maintaining tissue homeostasis but also contribute to …
important physiological functions in maintaining tissue homeostasis but also contribute to …
In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed
ID Vainchtein, J Vinet, N Brouwer, S Brendecke… - Glia, 2014 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous
system (CNS) characterized by loss of myelin accompanied by infiltration of T‐lymphocytes …
system (CNS) characterized by loss of myelin accompanied by infiltration of T‐lymphocytes …
Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
EN Benveniste - Journal of molecular medicine, 1997 - Springer
One of the characteristic features of microglia is their rapid activation in response to injury,
inflammation, neurodegeneration, infection, and brain tumors. This review focuses on the …
inflammation, neurodegeneration, infection, and brain tumors. This review focuses on the …
Differential roles of microglia and monocytes in the inflamed central nervous system
R Yamasaki, H Lu, O Butovsky, N Ohno… - Journal of Experimental …, 2014 - rupress.org
In the human disorder multiple sclerosis (MS) and in the model experimental autoimmune
encephalomyelitis (EAE), macrophages predominate in demyelinated areas and their …
encephalomyelitis (EAE), macrophages predominate in demyelinated areas and their …
Brain microglia and blood-derived macrophages: molecular profiles and functional roles in multiple sclerosis and animal models of autoimmune demyelinating …
G Raivich, R Banati - Brain Research Reviews, 2004 - Elsevier
Microglia and macrophages, one a brain-resident, the other a mostly hematogenous cell
type, represent two related cell types involved in the brain pathology in multiple sclerosis …
type, represent two related cell types involved in the brain pathology in multiple sclerosis …
The benefits and detriments of macrophages/microglia in models of multiple sclerosis
KS Rawji, VW Yong - Journal of Immunology Research, 2013 - Wiley Online Library
The central nervous system (CNS) is immune privileged with access to leukocytes being
limited. In several neurological diseases, however, infiltration of immune cells from the …
limited. In several neurological diseases, however, infiltration of immune cells from the …
Microglial cell activation and proliferation precedes the onset of CNS autoimmunity
ED Ponomarev, LP Shriver, K Maresz… - Journal of …, 2005 - Wiley Online Library
Microglial cells are central nervous system (CNS) resident cells that are thought to become
activated and contribute to the inflammation that occurs in the human autoimmune disease …
activated and contribute to the inflammation that occurs in the human autoimmune disease …
The role of microglia in multiple sclerosis
C Luo, C Jian, Y Liao, Q Huang, Y Wu… - Neuropsychiatric …, 2017 - Taylor & Francis
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS).
Microglia are the resident innate immune cells in the CNS; they play an important role in the …
Microglia are the resident innate immune cells in the CNS; they play an important role in the …