Background & Aim Human induced pluripotent stem cells (iPSCs) are emerging as a potent
starting material for allogeneic cell therapies. As a prerequisite, we have established a GMP …

Human induced pluripotent stem cells (iPSCs) can be limitlessly expanded and
differentiated into almost all cell types. Moreover, they are amenable to gene manipulation …

Natural killer (NK) cells are innate lymphocytes that play a key role in the control of infection
and malignancy. NK cells are potent killers of target cells and act in an MHC-independent …

Abstract Purpose of Review In the rapidly developing field of adoptive cell immunotherapy,
there is urgent need for discoveries that would improve outcomes, extend the applicability …

Select subsets of immune effector cells have the greatest propensity to mediate antitumor
responses. However, procuring these subsets is challenging, and cell-based …

The immune system plays a crucial role in recognizing and eliminating foreign antigens,
working in conjunction with other bodily systems to maintain the stability and physiological …

Mouse and human pluripotent stem cells have been widely used to study the development
of the hematopoietic and immune systems. Although not all cells can be derived with the …

Simple Summary Induced pluripotent stem cells (iPSCs) that can be genetically engineered
and differentiated into different types of immune cells, providing an unlimited resource for …

Cellular therapies combined with genetic engineering technologies have emerged as
increasingly powerful tools for immunotherapies of cancers and viral infections including HIV …

The discovery of human pluripotent stem cells (PSCs) at the turn of the century opened the
door to a new generation of regenerative medicine research. Among PSCs, the donors …