Background & Aim Induced pluripotent stem cells (iPSCs) are an ideal starting material for
cell-based therapies, however, manufacturing therapeutic cells from iPSCs has often been …

Background Dozens of transplants generated from pluripotent stem cells are currently in
clinical trials. The creation of patient-specific iPSCs makes personalized therapy possible …

Genetic reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs)
could offer replenishable cell sources for transplantation therapies. To fulfill their promises …

Induced pluripotent stem cells (iPSC) offer the possibility to generate diverse disease-
relevant cell types, from any genetic background with the use of cellular reprogramming and …

Conclusions Human induced pluripotent stem cells (hiPSCs) exhibit unlimited self-renewal
potential and have the capacity to differentiate into somatic cell derivatives of all three germ …

Natural killer (NK) cell-based adoptive immunotherapy is a promising treatment approach for
many cancers. However, development of protocols that provide large numbers of functional …

One of the major hurdles in realizing the therapeutic potential of human-induced pluripotent
stem cells (iPSC) is the generation of clinical-grade iPSC lines and their differentiated …

Induced pluripotent stem cells (iPSCs) hold immense potential in disease modeling, drug
discovery and regenerative medicine. Despite advances in reprogramming methods …

Human induced pluripotent stem cells (iPSCs) have emerged as an alternative source of
pluripotent stem cells that can be used for tissue regeneration in place of the controversial …

Treatments for B-cell malignancies have improved over the past several decades with
clinical application of the CD20-specific antibody rituximab and chimeric antigen receptor …