Coordinated induction of iNOS–VEGF–KDR–eNOS after resveratrol consumption: A potential mechanism for resveratrol preconditioning of the heart

S Das, VKT Alagappan, D Bagchi, HS Sharma… - Vascular …, 2005 - Elsevier
Existing evidence indicates that resveratrol, a red wine and grape-derived polyphenolic
antioxidant, can pharmacologically precondition the heart in a nitric oxide (NO)-dependent …

Pharmacological preconditioning with resveratrol: an insight with iNOS knockout mice

G Imamura, AA Bertelli, A Bertelli… - American Journal …, 2002 - journals.physiology.org
Resveratrol, a natural antioxidant and polyphenol found in grapes and wine, has been found
to pharmacologically precondition the heart through the upregulation of nitric oxide (NO). To …

Pharmacological preconditioning with resveratrol: role of nitric oxide

R Hattori, H Otani, N Maulik… - American Journal of …, 2002 - journals.physiology.org
Resveratrol (trans-3, 4′, 5-trihydroxystilbene), a recently described grape-derived
polyphenolic antioxidant, has been found to protect the heart from ischemic-reperfusion …

The red wine antioxidant resveratrol prevents cardiomyocyte injury following ischemia-reperfusion via multiple sites and mechanisms

SSC Goh, OL Woodman, S Pepe, AH Cao… - Antioxidants & redox …, 2007 - liebertpub.com
The objective was a comprehensive investigation of the mechanisms and sites of resveratrol
cardioprotection during and following ischemia–reperfusion (I–R) injury, and to determine …

Cardioprotective effect of resveratrol via HO-1 expression involves p38 map kinase and PI-3-kinase signaling, but does not involve NFκB

S Das, CG Fraga, DK Das - Free radical research, 2006 - search.ebscohost.com
Recent studies have demonstrated that resveratrol (trans-3, 4′, 5-trihydroxy stilbene), a
phytoalexin found in the skin and seeds of grapes, can pharmacologically precondition (PC) …

Resveratrol protects myocardial ischemia–reperfusion injury through both NO-dependent and NO-independent mechanisms

LM Hung, MJ Su, JK Chen - Free Radical Biology and Medicine, 2004 - Elsevier
We previously showed that resveratrol (3, 4′, 5-trihydroxystilbene) stimulates NO
production and is cardioprotective in rat heart subjected to ischemia–reperfusion (I/R rat …

RETRACTED: Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose

J Dudley, S Das, S Mukherjee, DK Das - 2009 - Elsevier
Recent studies have demonstrated the cardioprotective abilities of resveratrol, a
polyphenolic antioxidant present in red wine. Resveratrol can also kill cancer cells at …

Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1

S Fukuda, S Kaga, L Zhan, D Bagchi, DK Das… - Cell biochemistry and …, 2006 - Springer
In our study, resveratrol (polyphenol) has been identified as a very important stimulus/agent
for the induction of new vessel growth. Occlusion of a main coronary depletes the blood …

Resveratrol: a therapeutic promise for cardiovascular diseases

S Das, DK Das - Recent Patents on Cardiovascular Drug …, 2007 - ingentaconnect.com
The heart is an aerobic organ, and most of the energy required for the contraction and
maintenance of ion gradients comes from oxidative phosphorylation. Oxidative stress …

Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia

S Dernek, M Ikizler, N Erkasap, B Ergun… - Scandinavian …, 2004 - Taylor & Francis
Objective—The major objective of the present study is to evaluate the potential role of
resveratrol (RVT), a natural antioxidant found in grapes and red wine, in protecting the …