Intracellular transport by active diffusion
All substances exhibit constant random motion at the microscopic scale. This is a direct
consequence of thermal agitation, and leads to diffusion of molecules and small particles in …
consequence of thermal agitation, and leads to diffusion of molecules and small particles in …
Diffusion and directed motion in cellular transport
We study the motion of a probe driven by microtubule-associated motors within a living
eukaryotic cell. The measured mean square displacement,< x (t) 2> of engulfed 2 and 3 μ m …
eukaryotic cell. The measured mean square displacement,< x (t) 2> of engulfed 2 and 3 μ m …
Enhanced diffusion in active intracellular transport
We show that within a living eukaryotic cell, mean square displacement of an engulfed
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …
microsphere shows enhanced diffusion scaling as t 3/2 at short times, with a clear crossover …
Getting around the cell: physical transport in the intracellular world
Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …
complex intracellular milieu in order to deliver, distribute, and mix the many components that …
Cytoplasmic diffusion: molecular motors mix it up
CP Brangwynne, GH Koenderink… - The Journal of cell …, 2008 - rupress.org
Random motion within the cytoplasm gives rise to molecular diffusion; this motion is
essential to many biological processes. However, in addition to thermal Brownian motion …
essential to many biological processes. However, in addition to thermal Brownian motion …
Temporal analysis of active and passive transport in living cells
D Arcizet, B Meier, E Sackmann, JO Rädler… - Physical review letters, 2008 - APS
The cellular cytoskeleton is a fascinating active network, in which Brownian motion is
intercepted by distinct phases of active transport. We present a time-resolved statistical …
intercepted by distinct phases of active transport. We present a time-resolved statistical …
Anomalous transport in the crowded world of biological cells
F Höfling, T Franosch - Reports on Progress in Physics, 2013 - iopscience.iop.org
A ubiquitous observation in cell biology is that the diffusive motion of macromolecules and
organelles is anomalous, and a description simply based on the conventional diffusion …
organelles is anomalous, and a description simply based on the conventional diffusion …
Weak ergodicity breaking of receptor motion in living cells stemming from random diffusivity
Molecular transport in living systems regulates numerous processes underlying biological
function. Although many cellular components exhibit anomalous diffusion, only recently has …
function. Although many cellular components exhibit anomalous diffusion, only recently has …
Non-specific interactions govern cytosolic diffusion of nanosized objects in mammalian cells
The diffusivity of macromolecules in the cytoplasm of eukaryotic cells varies over orders of
magnitude and dictates the kinetics of cellular processes. However, a general description …
magnitude and dictates the kinetics of cellular processes. However, a general description …
Heterogeneities shape passive intracellular transport
A living cell's interior is one of the most complex and intrinsically dynamic systems, providing
an elaborate interplay between cytosolic crowding and ATP-driven motion that controls …
an elaborate interplay between cytosolic crowding and ATP-driven motion that controls …