Physics of transport and traffic phenomena in biology: from molecular motors and cells to organisms

D Chowdhury, A Schadschneider, K Nishinari - Physics of Life reviews, 2005 - Elsevier
Traffic-like collective movements are observed at almost all levels of biological systems.
Molecular motor proteins like, for example, kinesin and dynein, which are the vehicles of …

Diffusiophoresis in cells: A general nonequilibrium, nonmotor mechanism for the metabolism-dependent transport of particles in cells

RP Sear - Physical Review Letters, 2019 - APS
The more we learn about the cytoplasm of cells, the more we realize that the cytoplasm is
not uniform but instead is highly inhomogeneous. In any inhomogeneous solution, there are …

Experimental evidence of strong anomalous diffusion in living cells

N Gal, D Weihs - Physical Review E—Statistical, Nonlinear, and Soft …, 2010 - APS
We evaluated the transport of polymeric particles internalized into living cancer cells. The
mean-square displacement demonstrates superdiffusion with a scaling exponent of 1.25 …

Anomalous diffusion due to hindering by mobile obstacles undergoing Brownian motion or Orstein-Ulhenbeck processes

H Berry, H Chaté - Physical Review E, 2014 - APS
In vivo measurements of the passive movements of biomolecules or vesicles in cells
consistently report “anomalous diffusion,” where mean-squared displacements scale as a …

Heterogeneous anomalous transport in cellular and molecular biology

TA Waigh, N Korabel - Reports on Progress in Physics, 2023 - iopscience.iop.org
It is well established that a wide variety of phenomena in cellular and molecular biology
involve anomalous transport eg the statistics for the motility of cells and molecules are …

[HTML][HTML] Cytoplasmic RNA-protein particles exhibit non-Gaussian subdiffusive behavior

TJ Lampo, S Stylianidou, MP Backlund, PA Wiggins… - Biophysical journal, 2017 - cell.com
The cellular cytoplasm is a complex, heterogeneous environment (both spatially and
temporally) that exhibits viscoelastic behavior. To further develop our quantitative insight into …

[HTML][HTML] Enhanced reaction kinetics in biological cells

C Loverdo, O Bénichou, M Moreau, R Voituriez - Nature physics, 2008 - nature.com
The cell cytoskeleton is a striking example of an 'active'medium driven out-of-equilibrium by
ATP hydrolysis. Such activity has been shown to have a spectacular impact on the …

[HTML][HTML] Sampling the cell with anomalous diffusion—the discovery of slowness

G Guigas, M Weiss - Biophysical journal, 2008 - cell.com
Diffusion-mediated searching for interaction partners is an ubiquitous process in cell
biology. Transcription factors, for example, search specific DNA sequences, signaling …

Noisy continuous time random walks

JH Jeon, E Barkai, R Metzler - The Journal of Chemical Physics, 2013 - pubs.aip.org
Experimental studies of the diffusion of biomolecules within biological cells are routinely
confronted with multiple sources of stochasticity, whose identification renders the detailed …

[HTML][HTML] Anomalous diffusion of single particles in cytoplasm

BM Regner, D Vučinić, C Domnisoru, TM Bartol… - Biophysical journal, 2013 - cell.com
The crowded intracellular environment poses a formidable challenge to experimental and
theoretical analyses of intracellular transport mechanisms. Our measurements of single …