Non-equilibrium forces drive the anomalous diffusion of telomeres in the nucleus of mammalian cells

L Stadler, M Weiss - New Journal of Physics, 2017 - iopscience.iop.org
Telomeres are vital nucleotide sequences at both ends of each chromosome, and their
motion reports on the local dynamics of decondensed chromatin in the nucleus of interphase …

How molecular motors work in the crowded environment of living cells: coexistence and efficiency of normal and anomalous transport

I Goychuk, VO Kharchenko, R Metzler - PloS one, 2014 - journals.plos.org
Recent experiments reveal both passive subdiffusion of various nanoparticles and
anomalous active transport of such particles by molecular motors in the molecularly crowded …

A diffusiophoretic mechanism for ATP-driven transport without motor proteins

B Ramm, A Goychuk, A Khmelinskaia, P Blumhardt… - Nature Physics, 2021 - nature.com
The healthy growth and maintenance of a biological system depends on the precise spatial
organization of molecules within the cell through the dissipation of energy. Reaction …

Anomalous dynamics of cell migration

P Dieterich, R Klages, R Preuss… - Proceedings of the …, 2008 - National Acad Sciences
Cell movement—for example, during embryogenesis or tumor metastasis—is a complex
dynamical process resulting from an intricate interplay of multiple components of the cellular …

Gaussianity fair: the riddle of anomalous yet non-Gaussian diffusion

R Metzler - Biophysical journal, 2017 - cell.com
Single particle tracking has become a standard method, especially in biophysics (1, 2). With
superresolution microscopy, the motions of even individual molecules in a live cell are …

Probing microscopic origins of confined subdiffusion by first-passage observables

S Condamin, V Tejedor, R Voituriez… - Proceedings of the …, 2008 - National Acad Sciences
Subdiffusive motion of tracer particles in complex crowded environments, such as biological
cells, has been shown to be widespread. This deviation from Brownian motion is usually …

Hydrodynamic collective effects of active protein machines in solution and lipid bilayers

AS Mikhailov, R Kapral - Proceedings of the National …, 2015 - National Acad Sciences
The cytoplasm and biomembranes in biological cells contain large numbers of proteins that
cyclically change their shapes. They are molecular machines that can function as molecular …

Particle tracking in living cells: a review of the mean square displacement method and beyond

N Gal, D Lechtman-Goldstein, D Weihs - Rheologica Acta, 2013 - Springer
The focus of many particle tracking experiments in the last decade has been active systems,
such as living cells. In active systems, the particles undergo simultaneous active and …

Probing short-range protein Brownian motion in the cytoplasm of living cells

C Di Rienzo, E Gratton, F Beltram, F Cardarelli - Biophysical Journal, 2015 - cell.com
The translational motion of small molecules in cells appears to be suppressed compared to
what is observed in dilute solutions. Although, the rotation of small proteins is almost …

Migration of cells in a social context

S Vedel, S Tay, DM Johnston, H Bruus, SR Quake - Biophysical Journal, 2013 - cell.com
In multicellular organisms and complex ecosystems, cells migrate in a social context. While
this is essential for the basic processes of life such as embryonic development, wound …