Diffusion of solutes and macromolecules in aqueous cellular compartments is required for
numerous cellular processes including metabolism, second messenger signaling and …

Recent advances in cell biology enable precise molecular perturbations. The spatiotemporal
organization of cells and organisms, however, also depends on physical processes such as …

Collective migration of mechanically coupled cell layers is a notable feature of wound
healing, embryonic development, and cancer progression. In confluent epithelial sheets, the …

Diffusion in the plasma membrane of living cells is often found to display anomalous
dynamics. However, the mechanism underlying this diffusion pattern remains highly …

Mechanics of cancer cells are directly linked to their metastatic potential, or ability to produce
a secondary tumor at a distant site. Metastatic cells survive in the circulatory system in a non …

Active fluctuations, driven by processes that consume ATP, are prevalent in living cells and
are mostly driven by different forms of molecular motors. Such motors often move and …

We introduce the totally asymmetric simple exclusion process with Langmuir kinetics on a
network as a microscopic model for active motor protein transport on the cytoskeleton …

Intracellular transport is essential for maintaining proper cellular function in most eukaryotic
cells, with perturbations in active transport resulting in several types of disease. Efficient …

Cells continuously adapt to changing conditions through coordinated molecular and
mechanical responses. This adaptation requires the transport of molecules and signaling …

We discuss a quantitative influence of macromolecular crowding on biological processes:
motion, bimolecular reactions, and gene expression in prokaryotic and eukaryotic cells. We …