Viscoelasticity in homogeneous protein solutions

W Pan, L Filobelo, NDQ Pham, O Galkin, VV Uzunova… - Physical review …, 2009 - APS
We probe the transport properties in protein solutions stable with respect to any, solid or
liquid, phase separation as a step in the understanding of transport in the cytosol of live …

Diffusion within the cytoplasm: a mesoscale model of interacting macromolecules

F Trovato, V Tozzini - Biophysical journal, 2014 - cell.com
Recent experiments carried out in the dense cytoplasm of living cells have highlighted the
importance of proteome composition and nonspecific intermolecular interactions in …

Intracellular transport of insulin granules is a subordinated random walk

SMA Tabei, S Burov, HY Kim… - Proceedings of the …, 2013 - National Acad Sciences
We quantitatively analyzed particle tracking data on insulin granules expressing fluorescent
fusion proteins in MIN6 cells to better understand the motions contributing to intracellular …

Intracellular transport driven by cytoskeletal motors: General mechanisms and defects

C Appert-Rolland, M Ebbinghaus, L Santen - Physics Reports, 2015 - Elsevier
Cells are the elementary units of living organisms, which are able to carry out many vital
functions. These functions rely on active processes on a microscopic scale. Therefore, they …

Single particle tracking in systems showing anomalous diffusion: the role of weak ergodicity breaking

S Burov, JH Jeon, R Metzler, E Barkai - Physical Chemistry Chemical …, 2011 - pubs.rsc.org
Anomalous diffusion has been widely observed by single particle tracking microscopy in
complex systems such as biological cells. The resulting time series are usually evaluated in …

Diffusion-limited reactions in dynamic heterogeneous media

Y Lanoiselée, N Moutal, DS Grebenkov - Nature communications, 2018 - nature.com
Most biochemical reactions in living cells rely on diffusive search for target molecules or
regions in a heterogeneous overcrowded cytoplasmic medium. Rapid rearrangements of the …

Inferring diffusion in single live cells at the single-molecule level

A Robson, K Burrage… - … Transactions of the …, 2013 - royalsocietypublishing.org
The movement of molecules inside living cells is a fundamental feature of biological
processes. The ability to both observe and analyse the details of molecular diffusion in vivo …

Macromolecule diffusion and confinement in prokaryotic cells

JT Mika, B Poolman - Current opinion in biotechnology, 2011 - Elsevier
We review recent observations on the mobility of macromolecules and their spatial
organization in live bacterial cells. We outline the major fluorescence microscopy-based …

Memoryless self-reinforcing directionality in endosomal active transport within living cells

K Chen, B Wang, S Granick - Nature Materials, 2015 - nature.com
In contrast to Brownian transport, the active motility of microbes, cells, animals and even
humans often follows another random process known as truncated Lévy walk,. These …

Wanted: a positive control for anomalous subdiffusion

MJ Saxton - Biophysical journal, 2012 - cell.com
Anomalous subdiffusion in cells and model systems is an active area of research. The main
questions are whether diffusion is anomalous or normal, and if it is anomalous, its …