Patients with glioblastomas, the most common primary tumors of the central nervous system,
have poor prognoses because of uncontrolled tumor cell invasion and proliferation. β …

Abstract β-Catenin, a core component of Wnt/β-catenin signaling, has been shown to be a
crucial factor in a broad range of tumors, while its role in glioma is not well understood. In …

Abstract β‑catenin is a crucial oncogene that is capable of regulating cancer progression.
The aim of the present study was to clarify whether β‑catenin was associated with the …

Identification of molecular pathways that are essential for cancer cell survival is vital for
understanding the underlying biology, as well as to design effective cancer therapeutics. β …

In order to investigate the relationship between tyrosine phosphorylation of β-catenin and
transcriptional activity of β-catenin in Hela and Bcap-37 cells, genistein (a tyrosine kinase …

Angiogenesis is considered to play an important role in the development of malignant brain
tumors, especially glioblastoma multiforme (GBM). Abnormal vascular construction with a …

We have found that a malignant mesothelioma cell line, NCI-H28, had a chromosome 3p21.
3 homozygous deletion containing the β-catenin gene (CTNNB1), which suggested that the …

Glioblastoma multiforme (GBM) is a fast growing brain tumor characterized by extensive
infiltration into the surrounding tissue and one of the most aggressive cancers. GBM is the …

Background Previously, we found that treatment of LM8 murine osteosarcoma cells with
genistein, an isoflavone found in soy, increased the cellular level of β-catenin and …

Abstract Beta‐catenin (β‐catenin) is a multifunction protein with a central role in
physiological homeostasis. Its abnormal expression leads to various diseases including …