Purpose Idiopathic scoliosis is a complex developmental syndrome defined by an abnormal
structural curvature of the spine. High treatment costs, chronic pain/discomfort, and the need …

Abstract Background Idiopathic Scoliosis (IS) is the most common spinal deformity in
adolescents, accounting for 80% of all spinal deformities. However, the etiology remains …

Idiopathic scoliosis (IS), the most common spinal deformity, affects otherwise healthy
children and adolescents during growth. The aetiology is still unknown, although genetic …

Idiopathic scoliosis is a three-dimensional deformation of the spine. As its name suggests, its
pathogenesis remains poorly understood. Enhanced comprehension of its pathogenesis …

Although the exact etiology of adolescent idiopathic scoliosis is still undefined, genetic
factors play an important role. Some patients have familial genetic disease that appears to …

Adolescent idiopathic scoliosis (AIS) is the most common pediatric spinal deformity. Several
AIS susceptibility loci have been identified; however, they could explain only a small …

Idiopathic scoliosis (AIS) is the most common pediatric spinal deformity, affecting∼ 3% of
children worldwide. AIS significantly impacts national health in the US alone, creating …

Scoliosis is defined as the three-dimensional (3D) structural deformity of the spine with a
radiological lateral Cobb angle (a measure of spinal curvature) of≥ 10° that can be caused …

Idiopathic scoliosis in the adolescent period is a complex genetic disorder of high
prevalence and extreme variability. Epidemiological approaches have confirmed the genetic …

Adolescent idiopathic scoliosis (AIS) is an unexplained and common spinal deformity seen
in otherwise healthy children. Its pathophysiology is poorly understood despite intensive …