Resistance to activated protein C in women using oral contraceptives

M Spannagl, A Dick, A Assmann… - … in thrombosis and …, 1998 - thieme-connect.com
Resistance to activated protein C (APC resistance) is an important and common risk factor
for deep vein thrombosis. The majority of patients with APC resistance carry a mutation on …

Resistance to activated protein C, highly prevalent amongst users of oral contraceptives with venous thromboembolism

L Bennet, H Odeberg - Journal of internal medicine, 1998 - Wiley Online Library
Bennet L, Odeberg H (Blekinge Hospital, Karlskrona, Sweden). Resistance to activated
protein C, highly prevalent amongst users of oral contraceptives with venous …

Resistance to activated protein C, associated with oral contraceptives use; effect of formulations, duration of assumption, and doses of oestro-progestins

O Olivieri, S Friso, F Manzato, S Grazioli, F Bernardi… - Contraception, 1996 - Elsevier
Resistance to activated protein C (APC-R) is at present considered the most frequent
laboratory abnormality in patients with deep vein thrombosis. An increased risk for venous …

[HTML][HTML] Impact of progestagens on activated protein C (APC) resistance among users of oral contraceptives

M Alhenc‐Gelas, G Plu‐Bureau, S Guillonneau… - Journal of thrombosis …, 2004 - Elsevier
Oral contraceptive (OC) use is associated with an increased risk of venous
thromboembolism. Previous data reported higher thrombotic risk in women using third …

Plasma resistance to activated protein C: an important link between venous thromboembolism and combined oral contraceptives-a short review

J Jespersen - The European Journal of Contraception & …, 1996 - Taylor & Francis
The discovery of plasma resistance towards activated protein C, APC resistance, and its
main genetic background, the presence of a single-point mutation in the gene coding for …

Molecular biology and pathophysiology of APC resistance: current insights and clinical implications

J Rosing, HC Hemker, G Tans - Seminars in thrombosis and …, 1998 - thieme-connect.com
APC resistance is often associated with the occurrence of a single point mutation in factor V
(factor V Leiden) at a predominant cleavage site for the natural anticoagulant, activated …

[PDF][PDF] Acquired APC resistance related to oral contraceptives and pregnancy and its possible implications for clinical practice

JR Meinardi, CMA Henkensm, P Heringa… - Blood Coagulation and …, 1997 - Citeseer
Hereditary activated protein C (APC) resistance is an established risk factor of venous
thromboembolism, mostly associated with the Arg506-Gln mutation of the factor V gene [1]. A …

Acquired Activated Protein C Resistance in Postmenopausal Women Is Dependent on Factor Vlll: c Levels

R Marcucci, R Abbate, S Fedi… - American journal of …, 1999 - academic.oup.com
Activated protein C (APC) resistance is an established risk factor for venous
thromboembolism. In 5% to 10% of patients with venous thromboembolism, the APC …

Resistance to activated protein C as a basis for venous thromboembolism associated with pregnancy and oral contraceptives

M Hellgren, PJ Svensson, B Dahlbäch - American journal of obstetrics and …, 1995 - Elsevier
OBJECTIVE: Inherited resistance to activated protein C, which is caused by a single factor V
gene mutation, is a frequent risk factor for thrombosis. The purpose of this study was to …

Acquired APC resistance and oral contraceptives: differences between two functional tests

J Curvers, MCLGD Thomassen… - British journal of …, 1999 - Wiley Online Library
Resistance to activated protein C (APC) is often associated with a mutation in factor V (factor
VLeiden). Individuals without factor VLeiden who exhibit a response in functional APC …