Human bone marrow mesenchymal stem cells induce collagen production and tongue cancer invasion

S Salo, C Bitu, K Merkku, P Nyberg, IO Bello… - PLoS …, 2013 - journals.plos.org
Tumor microenvironment (TME) is an active player in carcinogenesis and changes in its
composition modify cancer growth. Carcinoma-associated fibroblasts, bone marrow-derived …

Interactions of human MSC with head and neck squamous cell carcinoma cell line PCI-13 reduce markers of epithelia-mesenchymal transition

F Böhrnsen, M Fricke, C Sander, A Leha… - Clinical Oral …, 2015 - Springer
Objectives Cancer progression is influenced by tumor microenvironment and
communication of stromal cells and tumor cells. Interactions may enhance epithelial …

Cancer-associated stromal cells promote the contribution of mmp2-positive bone marrow-derived cells to oral squamous cell carcinoma invasion

MW Oo, H Kawai, K Takabatake, Q Shan, HS Eain… - Cancers, 2021 - mdpi.com
Simple Summary Based on its invasiveness, oral squamous cell carcinoma (OSCC) shows
two different subtypes: less-invasive verrucous squamous carcinoma (VSCC) or highly …

Bone mesenchymal stem cells are recruited via CXCL8‐CXCR2 and promote EMT through TGF‐β signal pathways in oral squamous carcinoma

L Meng, Y Zhao, W Bu, X Li, X Liu, D Zhou… - Cell …, 2020 - Wiley Online Library
Objectives Bone mesenchymal stem cells (BMSCs) play critical roles in tumour
microenvironment. However, molecular mechanisms of how BMSCs to be recruited and …

The effects of mesenchymal stem cells on oral cancer and possible therapy regime

T Yang, S Tang, S Peng, G Ding - Frontiers in genetics, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs) are characterized by self-renewal, rapid proliferation,
multipotent differentiation, and low immunogenicity. In addition, the tropism of MSCs towards …

Mesenchymal stem cells derived from normal gingival tissue inhibit the proliferation of oral cancer cells in vitro and in vivo

X Ji, Z Zhang, Y Han, J Song, X Xu… - International …, 2016 - spandidos-publications.com
The interplay between tumor cells and mesenchymal stem cells (MSCs) within tumor
microenvironment plays a significant role in tumor development, and thus might be exploited …

Mesenchymal stem cells participate in oral mucosa carcinogenesis by regulating T cell proliferation

Y Chen, X Wang, J Fang, J Song, D Ma, L Luo, B He… - Clinical …, 2019 - Elsevier
Recent evidences suggested that Mesenchymal stem cells (MSCs) may be involved in tumor
formation by modulating of the tumor microenvironment, but it is still unclear the potential of …

BMSC–HNC Interaction: Exploring Effects on Bone Integrity and Head and Neck Cancer Progression

J Eichberger, D Froschhammer, D Schulz… - International Journal of …, 2023 - mdpi.com
In recent research, the tumor microenvironment has been shown to attract mesenchymal
stromal cells (MSCs), which is of particular interest due to its implications for cancer …

Crosstalk between cancer and different cancer stroma subtypes promotes the infiltration of tumor‑associated macrophages into the tumor microenvironment of oral …

Q Shan, K Takabatake, H Kawai… - International …, 2022 - spandidos-publications.com
Tumor‑associated macrophages (TAMs) are linked to the progression of numerous types of
cancer. However, the effects of the tumor microenvironment (TME) of oral squamous cell …

Stromal cells in the tumor microenvironment promote the progression of oral squamous cell carcinoma

Q Shan, K Takabatake, H Omori… - International …, 2021 - spandidos-publications.com
The stromal cells in the tumor microenvironment (TME) can influence the progression of
multiple types of cancer; however, data on oral squamous cell carcinoma (OSCC) are …