DNA methylation, genomic silencing, and links to nutrition and cancer

DC McCabe, MA Caudill - Nutrition reviews, 2005 - academic.oup.com
DNA methylation is a heritable epigenetic feature that is associated with transcriptional
silencing, X-chromosome inactivation, genetic imprinting, and genomic stability. The …

Epigenetic modifications and human pathologies: cancer and CVD

SJ Duthie - Proceedings of the Nutrition Society, 2011 - cambridge.org
Epigenetic changes are inherited alterations in DNA that affect gene expression and
function without altering the DNA sequence. DNA methylation is one epigenetic process …

[HTML][HTML] Methylation and the genome: the power of a small amendment

FD Urnov - The Journal of nutrition, 2002 - Elsevier
Methylation is a major regulator of mammalian genome function in vivo. The methylation of
DNA on cytosine residues is a critical component of the host genome defense pathway …

Methyl donor micronutrients that modify DNA methylation and cancer outcome

AM Mahmoud, MM Ali - Nutrients, 2019 - mdpi.com
DNA methylation is an epigenetic mechanism that is essential for regulating gene
transcription. However, aberrant DNA methylation, which is a nearly universal finding in …

DNA methylation, cancer susceptibility, and nutrient interactions

CD Davis, EO Uthus - Experimental biology and medicine, 2004 - journals.sagepub.com
DNA methylation is an important epigenetic mechanism of transcriptional control. DNA
methylation plays an essential role in maintaining cellular function, and changes in …

Diet and DNA methylation interactions in cancer prevention

SA Ross - Annals of the New York Academy of Sciences, 2003 - Wiley Online Library
Epigenetic events constitute an important mechanism by which gene function is selectively
activated or inactivated. Since epigenetic events are susceptible to change they offer …

[HTML][HTML] Assessing the effects of high methionine intake on DNA methylation

RA Waterland - The Journal of nutrition, 2006 - Elsevier
Methylation of DNA occurs at cytosines within CpG (cytosine-guanine) dinucleotides and is
1 of several epigenetic mechanisms that serve to establish and maintain tissue-specific …

Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation

OS Anderson, KE Sant, DC Dolinoy - The Journal of nutritional …, 2012 - Elsevier
DNA methylation is the most extensively studied mechanism of epigenetic gene regulation.
Increasing evidence indicates that DNA methylation is labile in response to nutritional and …

The role of DNA methylation in ageing and cancer

AE Morgan, TJ Davies, MT Mc Auley - Proceedings of the Nutrition …, 2018 - cambridge.org
The aim of the present review paper is to survey the literature related to DNA methylation,
and its association with cancer and ageing. The review will outline the key factors, including …

DNA methylation in cancer: epigenetic view of dietary and lifestyle factors

M Maleknia, N Ahmadirad, F Golab… - Epigenetics …, 2023 - journals.sagepub.com
Background: Alterations in DNA methylation play an important role in cancer development
and progression. Dietary nutrients and lifestyle behaviors can influence DNA methylation …