Commentary: evaluation of models of Parkinson's disease

PC Leal, LCRF Lins, AM De Gois… - Frontiers in …, 2016 - frontiersin.org
In the recently published review article by Jagmag et al.(2016), some currently available
neurotoxin based and genetic models of Parkinson's disease (PD) were described …

Evaluation of models of Parkinson's disease

SA Jagmag, N Tripathi, SD Shukla, S Maiti… - Frontiers in …, 2016 - frontiersin.org
Parkinson's disease is one of the most common neurodegenerative diseases. Animal
models have contributed a large part to our understanding and therapeutics developed for …

Commentary: evaluation of models of Parkinson's disease

P Muñoz, I Paris, J Segura-Aguilar - Frontiers in Neuroscience, 2016 - frontiersin.org
This publication is a review on the preclinical model used today for Parkinson's disease that
take in consideration both preclinical model based on neurotoxin or mutations associated to …

Neurotoxin-induced animal models of Parkinson disease: pathogenic mechanism and assessment

XS Zeng, WS Geng, JJ Jia - ASN neuro, 2018 - journals.sagepub.com
Parkinson disease (PD) is the second most common neurodegenerative movement
disorder. Pharmacological animal models are invaluable tools to study the pathological …

Neurotoxin-induced rodent models of Parkinson's disease: benefits and drawbacks

M El-Gamal, M Salama, LE Collins-Praino, I Baetu… - Neurotoxicity …, 2021 - Springer
Abstract Parkinson's disease (PD), the second most common neurodegenerative disorder, is
characterized by cardinal motor impairments, including akinesia and tremor, as well as by a …

Experimental models of Parkinson's disease: challenges and opportunities

R Lal, K Chopra - European Journal of Pharmacology, 2024 - Elsevier
Parkinson's disease (PD) is a widespread neurodegenerative disorder occurs due to the
degradation of dopaminergic neurons present in the substantia nigra pars compacta (SNpc) …

Classic and evolving animal models in Parkinson's disease

T Pingale, GL Gupta - Pharmacology Biochemistry and Behavior, 2020 - Elsevier
Parkinson's disease (PD) is a progressive neurodegenerative disease with motor and non-
motor symptoms. PD is characterized by the degeneration of dopaminergic neurons in the …

Animal models for Parkinson's disease research: trends in the 2000s

K Kin, T Yasuhara, M Kameda, I Date - International journal of molecular …, 2019 - mdpi.com
Parkinson's disease (PD) is a chronic and progressive movement disorder and the second
most common neurodegenerative disease. Although many studies have been conducted …

Neurotoxin-based models of Parkinson's disease

J Bové, C Perier - Neuroscience, 2012 - Elsevier
Animal experimentation in the Parkinson's disease (PD) field is a classic example of how the
use of animal models to study diseases can have a significant impact on human health …

[HTML][HTML] Parkinson's disease: animal models and dopaminergic cell vulnerability

J Blesa, S Przedborski - Frontiers in neuroanatomy, 2014 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …