Phase III randomized trial comparing three platinum-based doublets in advanced non–small-cell lung cancer

GV Scagliotti, F De Marinis, M Rinaldi… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: To evaluate whether two commonly used newer platinum-based regimens offer
any advantage over vinorelbine-cisplatin (reference regimen) in response rate for patients …

Cisplatin plus gemcitabine versus a cisplatin-based triplet versus nonplatinum sequential doublets in advanced non–small-cell lung cancer: A Spanish Lung Cancer …

V Alberola, C Camps, M Provencio, D Isla… - Journal of clinical …, 2003 - ascopubs.org
Purpose: To compare the survival benefit obtained with cisplatin plus gemcitabine, a
cisplatin-based triplet, and nonplatinum sequential doublets in advanced non–small-cell …

[HTML][HTML] Addition of platinum compounds to a new agent in patients with advanced non-small-cell lung cancer: a literature based meta-analysis of randomised trials

K Hotta, K Matsuo, H Ueoka, K Kiura, M Tabata… - Annals of oncology, 2004 - Elsevier
Background Single new agents reportedly produce promising response and survival effects,
but platinum-based doublets remain the standard chemotherapy for advanced non-small …

[HTML][HTML] Single-agent versus combination chemotherapy in patients with advanced non-small cell lung cancer and a performance status of 2: prognostic factors and …

R Lilenbaum, VM Villaflor, C Langer, K O'Byrne… - Journal of Thoracic …, 2009 - Elsevier
Purpose: Data from two randomized phase III trials were analyzed to evaluate prognostic
factors and treatment selection in the first-line management of advanced non-small cell lung …

Should chemotherapy combinations for advanced non-small cell lung cancer be platinum-based? A meta-analysis of phase III randomized trials

JL Pujol, F Barlesi, JP Daurès - Lung cancer, 2006 - Elsevier
BACKGROUND: Non-platinum regimens have been proposed as an alternative to the
platinum-based combinations for treatment of advanced non-small cell lung cancer …

Platinum-based versus non-platinum-based chemotherapy in advanced non-small-cell lung cancer: a meta-analysis of the published literature

G D'Addario, M Pintilie, NB Leighl, R Feld… - Journal of clinical …, 2005 - ascopubs.org
Purpose This meta-analysis was performed to compare the activity, efficacy and toxicity of
platinum-based versus non-platinum-based chemotherapy in patients with advanced non …

Efficacy and side effects of cisplatin-and carboplatin-based doublet chemotherapeutic regimens versus non-platinum-based doublet chemotherapeutic regimens as …

A Rajeswaran, A Trojan, B Burnand, M Giannelli - Lung cancer, 2008 - Elsevier
Evidence suggests that platinum-based regimens confer a better survival in patients with
non-small cell lung carcinoma (NSCLC). However, evidence is lacking regarding the …

Single-agent versus combination chemotherapy in advanced non–small-cell lung cancer: The Cancer and Leukemia Group B (study 9730)

RC Lilenbaum, JE Herndon, MA List… - Journal of Clinical …, 2005 - ascopubs.org
Purpose We compared the efficacy of combination chemotherapy versus single-agent
therapy in patients with advanced non–small-cell lung cancer. Patients and Methods A total …

First-line treatment for advanced non-small-cell lung cancer.

JJ Laskin, AB Sandler - Oncology (Williston Park, NY), 2005 - europepmc.org
With best supportive care alone, patients with metastatic non-small-cell lung cancer
(NSCLC) have a median survival of 4 to 5 months and a 1-year survival rate of …

Single agent versus combination chemotherapy in patients with advanced nonsmall cell lung carcinoma: A meta‐analysis of response, toxicity, and survival

RC Lilenbaum, P Langenberg… - … International Journal of …, 1998 - Wiley Online Library
BACKGROUND This meta‐analysis was conducted to compare the effects of single agent
versus combination chemotherapy on response rate, toxicity, and survival of patients with …