Synthetic derivatives of the α-and β-amyrin triterpenes and their antinociceptive properties
Fifteen different derivatives of an α-and β-amyrin mixture were synthesized by acylation with
appropriate anhydride or acid chlorides and oxidation in the presence of tert-butyl chromate …
appropriate anhydride or acid chlorides and oxidation in the presence of tert-butyl chromate …
The pentacyclic triterpenes α, β-amyrins: A review of sources and biological activities
L Hernández-Vázquez… - Chapter 23 in: Rao …, 2012 - diposit.ub.edu
Pentacyclic triterpenes are ubiquitously distributed throughout the plant kingdom, in a free
form as aglycones or in combined forms, and have long been known to have a number of …
form as aglycones or in combined forms, and have long been known to have a number of …
Quantification of α‐and β‐amyrin in rat plasma by gas chromatography–mass spectrometry: application to preclinical pharmacokinetic study
Abstract α‐and β‐Amyrins are naturally occurring triterpenes with a wide range of biological
activities. In this study, a reliable GC‐MS method was developed and validated for the …
activities. In this study, a reliable GC‐MS method was developed and validated for the …
Analgesic and Anti-Inflammatory Activities of the Isomeric Mixture of Alpha- and Beta-Amyrin from Protium heptaphyllum(Aubl.) March
GF Aragao, MCC Pinheiro, PN Bandeira… - Journal of herbal …, 2008 - Taylor & Francis
In the present work, we demonsteated that the mixture of alpha-and beta-amyrin (AMI) from
Protium heptaphyllum has anti-nociceptive activity as was evident from the writhing and …
Protium heptaphyllum has anti-nociceptive activity as was evident from the writhing and …
Antinoceptive effect of triterpenoid α, β-amyrin in rats on orofacial pain induced by formalin and capsaicin
SAH Pinto, LMS Pinto, MA Guedes, GMA Cunha… - Phytomedicine, 2008 - Elsevier
The effects of α, β-amyrin, a pentacyclic triterpene isolated from Protium heptaphylum was
investigated on rat model of orofacial pain induced by formalin or capsaicin. Rats were …
investigated on rat model of orofacial pain induced by formalin or capsaicin. Rats were …
Contribution of α,β‐Amyrenone to the Anti‐Inflammatory and Antihypersensitivity Effects of Aleurites moluccana (L.) Willd.
NLM Quintão, LW Rocha, GF Silva… - BioMed Research …, 2014 - Wiley Online Library
The aim of the study was to analyze the constituents of the dichloromethane fraction
obtained from A. moluccana and also to evaluate the anti‐inflammatory and antinociceptive …
obtained from A. moluccana and also to evaluate the anti‐inflammatory and antinociceptive …
Pharmacological effects of the isomeric mixture of alpha and beta amyrin from Protium heptaphyllum: a literature review
AO Nogueira, YIS Oliveira, BL Adjafre… - Fundamental & …, 2019 - Wiley Online Library
Protium heptaphyllum Aubl. belongs to the Burseraceae family. It is commonly called
'almecegueira'and is known to produce an amorphous resin which has constituents such as …
'almecegueira'and is known to produce an amorphous resin which has constituents such as …
Evidence for excitatory and inhibitory amino acids participation in the neuropharmacological activity of alpha-and beta-amyrin acetate
GF Aragão, L MV Carneiro, A PF Juniora… - The Open …, 2009 - benthamopen.com
We evaluated the neuropharmacological profile of acetylated alpha-and beta-amyrin
(AcAMY) obtained by the acetylation of the isomeric mixture of alpha-and beta-amyrin …
(AcAMY) obtained by the acetylation of the isomeric mixture of alpha-and beta-amyrin …
Synthesis of biologically active N-methyl derivatives of amidines and cyclized five-membered products of amidines with oxalyl chloride
SM Sondhi, M Dinodia, S Jain, A Kumar - European journal of medicinal …, 2008 - Elsevier
A series of substituted N-methylisonicotinamidine (2a–f), N-methylpyrazine-2-carboxamidine
(2g–i) derivatives were synthesized by reaction of amidine derivatives (1a–i) with methyl …
(2g–i) derivatives were synthesized by reaction of amidine derivatives (1a–i) with methyl …
A non-michaelian behavior of the in vitro metabolism of the pentacyclic triterpene alfa and beta amyrins by employing rat liver microsomes
F de Lima Moreira, GHB de Souza, IV Rodrigues… - … of pharmaceutical and …, 2013 - Elsevier
Pharmacological studies employing alpha and beta amyrin have demonstrated potential
application in several biological activities suggesting their application as promising drugs. In …
application in several biological activities suggesting their application as promising drugs. In …