Andrographolide (AD) is the main compound distributed in medicinal herb Andrographis
paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of …

Ethnopharmacological relevance Traditional plant-derived medicines have enabled the
mankind in curing the wide spectrum of diseases throughout the ages. Andrographis …

As the main active constituent of Andrographis paniculata that was applied in treatment of
many diseases including inflammation in ancient China, andrographolide (ANDRO) was …

Botanicals have attracted much attention in the field of anti-inflammatory due to their good
pharmacological activity and efficacy. Andrographis paniculata is a natural plant ingredient …

Andrographis paniculata has long been part of the traditional herbal medicine system in
Asia and in Scandinavia. Andrographolide was isolated as a major bioactive constituent of …

Andrographolide, a diterpenoid lactone obtained from plant Andrographis paniculata, is
used in South Asian countries to relieve various inflammatory symptoms. To study the effects …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by symmetric
polyarthritis with swelling and pain at synovial joints. In RA patients, delayed neutrophil …

Background Andrographolide (AD) has been reported to play a potential anti-arthritic role by
facilitating the proliferation and inhibiting the apoptosis of chondrocytes. However, the …

Objective The aim of this study was to investigate the effects of andrographolide on matrix
metalloproteinases (MMP) 1, 3, and 13 and inducible nitric oxide synthase (iNOS) in human …

Background Synovial inflammation plays a major role in the pathogenesis of osteoarthritis
(OA). This study investigated the effect of andrographolide (Andro) on synovial inflammation …