Bacterial resistance to commonly used drugs has become a global health problem, causing
increased infection cases and mortality rate. One of the main virulence determinants in many …

The increasing prevalence of persistent biofilm infections, such as wound infections, chronic
lung infections or medical device-related infections, which usually tolerate conventional …

The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …

Biofilms form a complex layer with defined structures, that attach on biotic or abiotic surfaces,
are tough to eradicate and tend to cause some resistance against most antibiotics. Several …

Bacterial resistance is an emergency public health problem worldwide, compounded by the
ability of bacteria to form biofilms, mainly in seriously ill hospitalized patients. The World …

It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …

The “golden era” of antibiotic discovery has long passed, but the need for new antibiotics
has never been greater due to the emerging threat of antibiotic resistance. This urgency to …

The formation of surface-attached cellular agglomerates, the so-called biofilms, contributes
significantly to bacterial resistance to antibiotics and innate host defenses. Bacterial biofilms …

Microbial cells show a strong natural tendency to adhere to surfaces and to colonize them by
forming complex communities called biofilms. In this growth mode, biofilm-forming cells …

The rapid increase in drug-resistant infections has presented a serious challenge to
antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” …