Cytogenic analysis of leukemic cells has proven to be a mandatory part of the diagnosis of
malignant hemopathies. Recurring clonal cytogenetic abnormalities may be divided into …

Conventional cytogenetic studies are widely used today to diagnose and manage patients
with hematological malignancies. The application of fluorescence in situ hybridization (FISH) …

Cytogenomic investigations of haematological neoplasms, including chromosome banding
analysis, fluorescence in situ hybridisation (FISH) and microarray analyses have become …

Abstract Background and Aims: Diagnosing hematologic malignancies requires
implementing several tests. This study aims to evaluate the chromosomal changes in …

The information obtained by conventional cytogenetics (CC) in human leukemias is
sometimes limited, in particular by complex karyotypes with many marker chromosomes …

During the last five decades, chromosome analysis identified recurring translocations and
inversions in leukemias and lymphomas, which led to cloning of genes at the breakpoints …

Objective: Hematological cancers are a group of neoplasms that affect the bone marrow,
blood and lymph nodes, usually associated with structural and numerical chromosomal …

Classical cytogenetic studies provide a global overview of acquired genetic changes in
patients with hematologic malignancies. The information obtained may be diagnostic or …

In the last decade the improvement of methods of chromosome analysis has allowed new
insights into the correlation of specific chromosome changes and certain types of malignant …