Eighty-nine patients who developed a secondary hematologic disorder and were studied
with chromosome analysis were collected from nine institutions. The results of the study …

Background: Chromosomal aberrations which occur in different hematologic malignancies
are believed to be highly applicable for identifying the prognosis and treatment protocols …

Abstract Analysis of most hematologic neoplasms indicates the involvement of one or more
cell lineages in the bone marrow and/or the blood but rules out the involvement of all …

Peripheral blood (PB) is sometimes used in place of bone marrow (BM) for cytogenetic
studies during the evaluation of hematologic malignancies. A total of 242 PB cytogenetic …

ABSTRACT Introduction: Conventional Cytogenetics is an essential tool for the diagnosis of
a neoplastic or premalignant condition and provides important prognostic and therapeutic …

Complex karyotype (CK) in patients with myelodysplastic syndrome (MDS) and acute
myeloid leukemia (AML) is a factor of unfavorable prognosis, associated with high frequency …

The correct enumeration of human chromosomes, only established in 1956, has marked the
starting point of the modern cytogenetics. The introduction of banding techniques, then of in …

Leukemia comprises a heterogeneous group of hematological neoplasias characterized by
clonal proliferation of hematopoietic cell lineages that underwent genetic alterations, leading …

Bone marrow transplantation (BMT) is a therapeutic process used to treat a variety of
hematologic diseases. After BMT, the documentation of engrafting with the use of genetic …

Al director: Desde el hallazgo de la presencia del gen de fusión BCR-ABL como producto
de la translocación entre los cromosomas 9 y 22 presente en la leucemia mieloide crónica …