Acetate supplementation eliminates hypoxia mediated resistance to differentiation therapy in neuroblastoma cells
Neuroblastoma is the most common extracranial solid tumor in childhood. Retinoic acid (RA)
leads to cell cycle arrest and induces cell differentiation in neuroblastoma cells, thus it has …
leads to cell cycle arrest and induces cell differentiation in neuroblastoma cells, thus it has …
The role of anlotinib-mediated EGFR blockade in a positive feedback loop of CXCL11-EGF-EGFR signalling in anaplastic thyroid cancer angiogenesis
J Liang, Z Jin, J Kuang, H Feng, Q Zhao, Z Yang… - British journal of …, 2021 - nature.com
Background Hypoxia-induced angiogenesis functions importantly in anaplastic thyroid
cancer (ATC) progression. However, the therapeutic potential of broad-spectrum anti …
cancer (ATC) progression. However, the therapeutic potential of broad-spectrum anti …
Role of sodium/iodide symporter overexpression in inhibiting thyroid cancer cell invasion and stem cell maintenance by inhibiting the β-catenin/LEF-1 pathway
NF Luo, JL Li, J Lv, FK Chen, YN Li, M Tang, PJ Liu - Heliyon, 2024 - cell.com
Background In thyroid cancers, a reduction in the expression of the sodium/iodide symporter
(NIS) is observed concomitant with a diminution in cancer cell differentiation. The β …
(NIS) is observed concomitant with a diminution in cancer cell differentiation. The β …
[HTML][HTML] Anticancer effects of natural phytochemicals in anaplastic thyroid cancer
Y Li, J Zhang, H Zhou, Z Du - Oncology Reports, 2022 - spandidos-publications.com
Anaplastic thyroid cancer (ATC) is an aggressive and lethal malignancy having a dismal
prognosis. Phytochemicals are bioactive components obtained from plants that have been …
prognosis. Phytochemicals are bioactive components obtained from plants that have been …
Anoikis-related genes combined with single cell sequencing: Insights into model specification of lung adenocarcinoma and applicability for prognosis and therapy
Y Zhou, Z Hu - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Background: Anoikis has therapeutic potential against different malignancies including lung
adenocarcinoma. This study used anoikis and bioinformatics to construct a prognostic model …
adenocarcinoma. This study used anoikis and bioinformatics to construct a prognostic model …
Knockdown of ANXA10 inhibits proliferation and promotes apoptosis of papillary thyroid carcinoma cells by down-regulating TSG101 thereby inactivating the MAPK …
T Wei, X Zhu - Journal of Bioenergetics and Biomembranes, 2021 - Springer
Abstract Annexin A10 (ANXA10) is a member of annexin A and has been reported to highly
express in papillary thyroid carcinoma (PTC) tissues. Tumor susceptibility gene 101 …
express in papillary thyroid carcinoma (PTC) tissues. Tumor susceptibility gene 101 …
Synergistic effect of metformin and vemurufenib (PLX4032) as a molecular targeted therapy in anaplastic thyroid cancer: an in vitro study
L Durai, S Ravindran, K Arvind, D Karunagaran… - Molecular Biology …, 2021 - Springer
Background Survival rate of patients affected with anaplastic thyroid carcinoma (ATC) is less
than 5% with current treatment. In ATC, BRAF V600E mutation is the major mutation that …
than 5% with current treatment. In ATC, BRAF V600E mutation is the major mutation that …
[HTML][HTML] A novel anoikis-related gene signature to predict the prognosis, immune infiltration, and therapeutic outcome of lung adenocarcinoma
Y Wang, C Xie, Y Su - Journal of Thoracic Disease, 2023 - ncbi.nlm.nih.gov
Background Lung cancer is a highly aggressive disease and the leading cause of cancer-
related deaths. Lung adenocarcinoma (LUAD) is the most common histological subtype of …
related deaths. Lung adenocarcinoma (LUAD) is the most common histological subtype of …
Prolonged survival of anaplastic thyroid carcinoma is associated with resectability, low tumor-infiltrating neutrophils/myeloid-derived suppressor cells, and low …
Purpose Anaplastic thyroid carcinoma (ATC) is the most lethal form of thyroid cancer with
most patients dying of their disease within a few months. Only a very small percentage of …
most patients dying of their disease within a few months. Only a very small percentage of …
Mechanisms for modulating anoikis resistance in cancer and the relevance of metabolic reprogramming
FO Adeshakin, AO Adeshakin, LO Afolabi, D Yan… - Frontiers in …, 2021 - frontiersin.org
The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …
stability and well-being. ECM detachment in localized tumors precedes abnormal …